Protein Alignment CG10444 and SLC5A7

DIOPT Version :9

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001291934.1
• Gene: SLC5A7 / 60482
• HGNCID: 14025
• Length: 580
• Species: Homo sapiens
• Alignment Length: 639
• Identity: 125/639 - (19%)
• Similarity: 257/639 - (40%)
• Gaps: 171/639 - (26%)

  Fly    12 AVLITILVISALIGIYYRY----TGGKQKTTQEYLMADQSMTTFPVSFSLMASFMSAISLMGVSN 72
            |:::..|:| .|:||:..:    :|..::.::..::..:.:......|::.|:::....:.|.:.
Human    10 AIIVFYLLI-LLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAE 73

  Fly    73 ESY--EFGTIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERRFGQATRLSASLAFTVQM 135
            ..|  .:|..:....|.|.||..:...||..........::.:..::.:|:.
Human    74 AVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKR------------- 125

  Fly   136 VLYMGIALYAPAL----------------ALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLIT 184
               ||..|:.|||                .:..:..:...:::::..|:.|.|:.:|||.:|..|
Human   126 ---MGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYT 187

  Fly   185 DVFQSFLMFAAIYAVI--AVS--AIKAGGFAAI-------WDVAVERGRVNFIEFSLDPTVRHTW 238
            ||.|.|.:|..::..:  |:|  |:...||.|:       |...|:...|            ::|
Human   188 DVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEV------------YSW 240

  Fly   239 WS----LIIGGMVTYLSLYGVNQTQVQRLLS--------VRNLKSAQSALWWNLP--ILGMLSFS 289
            ..    |::||:..        |...||:||        |.:..:|...|...:|  ::|.:..|
Human   241 LDSFLLLMLGGIPW--------QAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGAS 297

  Fly   290 TIFSGLSIFYYYRDCDPLLKGRIDKRDQIMPLFALETMGQYPGLCGLFVS--GIFSASLSTISSA 352
            |.::..:    |...||   ...::.|.|:|:..     ||  ||.:::|  |:.:.|.:.:|||
Human   298 TDWNQTA----YGLPDP---KTTEEADMILPIVL-----QY--LCPVYISFFGLGAVSAAVMSSA 348

  Fly   353 VTS-LSAVTLEDYLKPLYKAIFKRTLIDSKSTMPTKIVACIFGLLCIGLAFVAGSMGGVLQASLT 416
            .:| |||.::  :.:.:|:..|::...|.:.....:|...:||.....:|.:..::.|:...|..
Human   349 DSSILSASSM--FARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSD 411

  Fly   417 IFGVVGGP--LLAIFTLGVCTTRSNQRGVLLGFLVSLIVSFWMGFGGPKP----KPVTLEFSTAG 475
            :..:|..|  |..:|..|     :|..|.:.|::..|    ::...|.:|    :|
Human   412 LVYIVIFPQLLCVLFVKG-----TNTYGAVAGYVSGL----FLRITGGEPYLYLQP--------- 458

  Fly   476 CENATAVMARAIELSSKSSGVVIEPDYF----WLYRISYLWLSVIGFLIAVVVGYFSSIVLAHCG 536
                                ::..|.|:    .:|...:.:.:     :|:|..:.::|.:::..
Human   459 --------------------LIFYPGYYPDDNGIYNQKFPFKT-----LAMVTSFLTNICISYLA 498

  Fly   537 KAENAEIYL-DKSRKQLDYDLFAPMLSRRWRRHKEE-QDQT--AQDETLTKLTE 586
            |      || :........|:|..:::    ||.|| .|:|  .::|.: ||.|
Human   499 K------YLFESGTLPPKLDVFDAVVA----RHSEENMDKTILVKNENI-KLDE 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	109/578 (19%)
SLC5A7	NP_001291934.1	SLC5sbd_CHT	8..495	CDD:271368	110/580 (19%)
		Mediates interaction with SEC14L1. /evidence=ECO:0000250|UniProtKB:Q9JMD7	502..580		12/45 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810