Protein Alignment CG10444 and Slc5a8

DIOPT Version :10

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001178916.1
• Gene: Slc5a8 / 500820
• RGDID: 1564146
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 575
• Identity: 239/575 - (41%)
• Similarity: 355/575 - (61%)
• Gaps: 33/575 - (5%)

  Fly     3 VGTFDAWDAAVLITILVISALIGIYYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFMSAISL 67
            :|:|..||..|...:|:|||.|||||.:.||.|:|::::||..:||:..||:.||.||||||:::
  Rat     7 IGSFVVWDYVVFAGMLLISAAIGIYYAFAGGGQQTSKDFLMGGRSMSAVPVALSLTASFMSAVTV 71

  Fly    68 MGVSNESYEFGTIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERRFGQATRLSASLAFT 132
            :|...|.|.||.||.:..:.|.....|:|..|||||||:..||.|||||.||.:..||..::.|.
  Rat    72 LGTPAEVYRFGAIFSIFGVTYFFVVVISAEVFLPVFYRLGITSTYEYLELRFNRFIRLCGTVLFI 136

  Fly   133 VQMVLYMGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQSFLMFAAIY 197
            ||.:||.||.:|||||||..|||.....|:|..|:|||||.||||||||:.|||||..:|.|...
  Rat   137 VQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVVWTDVFQVGIMVAGFA 201

  Fly   198 AVIAVSAIKAGGFAAIWDVAVERGRVNFIEFSLDPTVRHTWWSLIIGGMVTYLSLYGVNQTQVQR 262
            :||..::|..||...|...|...||:||..|:.:|..|||:|::|:||..|:.::|||||:||||
  Rat   202 SVIIQASITQGGINTILSDASNGGRLNFWNFNPNPLQRHTFWTIIVGGTFTWTTIYGVNQSQVQR 266

  Fly   263 LLSVRNLKSAQSALWWNLPILGMLSFSTIFSGLSIFYYYRDCDPLLKGRIDKRDQIMPLFALETM 327
            .:|.::...|:.:|:.||..|.::...::|.||:::..|.||||....::.:.||:||...|:.:
  Rat   267 YISCKSRLHAKLSLYVNLVGLWVILICSVFCGLALYSRYHDCDPWTSKKVSEVDQLMPYLVLDIL 331

  Fly   328 GQYPGLCGLFVSGIFSASLSTISSAVTSLSAVTLEDYLKPLYKAIFKRTLIDSKSTMPTKIVACI 392
            ..|||:.||||:..:|.:|||:||::.:|:|||:||.:||.:|::.:::|     :..::.::.:
  Rat   332 KNYPGVPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPRFKSLSEKSL-----SWISQGMSVL 391

  Fly   393 FGLLCIGLAFVAGSMGGVLQASLTIFGVVGGPLLAIFTLGVCTTRSNQRGVLLGFLVSLIVSFWM 457
            :|.||||:|.||..||.:|||:|:|||:||||||.:|:||:....:|..|...|.|....||.|:
  Rat   392 YGALCIGMAAVASLMGALLQAALSIFGMVGGPLLGLFSLGILVPFANSVGAFAGLLAGFAVSLWV 456

  Fly   458 GFGG----PKPK---PVTLEFSTAGC---ENATAVMA--------RAIELSSKSSGVVIEPDYFW 504
            |.|.    |.|:   |::||  |.||   .|.|..|:        .|.::.......:::.   |
  Rat   457 GIGAQLYPPLPERTLPLSLE--THGCNSTHNGTDWMSTTEMPFSTSAFQIHDVERSALMDN---W 516

  Fly   505 LYRISYLWLSVIGFLIAVVVGYFSSIVLAHCGKAENAE--IYLDKSRKQLDYDLF 557
             |.:|||:.|.||.|..::||..  |.||..|:.:|.:  ..|.|.....::|:|
  Rat   517 -YSLSYLYFSTIGTLTTLLVGIL--ISLATGGRKQNLDPRFLLTKQDFLSNFDVF 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	228/539 (42%)
Slc5a8	NP_001178916.1	SLC5sbd_SMCT1	7..549	CDD:271402	234/554 (42%)