DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10444 and SPBPB8B6.02c

DIOPT Version :9

Sequence 1:	NP_611465.2	Gene:	CG10444 / 37294	FlyBaseID:	FBgn0034494	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001018763.1	Gene:	SPBPB8B6.02c / 3361185	PomBaseID:	SPBPB8B6.02c	Length:	673	Species:	Schizosaccharomyces pombe

Alignment Length:	552	Identity:	116/552 - (21%)
Similarity:	224/552 - (40%)	Gaps:	111/552 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 AVLITIL--VISALIGIYYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFMSAISLMGVSNES 74
            |:|:.|:  |::|.:        |:.:.::.:..|.:|:.:..:|.|.::::....:|:.....|
pombe    22 ALLMAIITKVLTACM--------GQTQNSERFSTASRSVKSGLISSSTVSAWTWPATLLSSGAWS 78

  Fly    75 YEFGTIFCVINIAYVL--STPIAAYFFLPVFYRMRTTSVYEYLE---RRFGQATRLSASLAFTVQ 134
            |.:|.:.   ...|.:  :..|..:.||.:..:.:..:.:...|   .|||:       |...|.
pombe    79 YTYGIMG---GFMYGVGGTIQITLFLFLAIQIKKKAPAAHTVSECFFIRFGK-------LGHCVY 133

  Fly   135 M-------VLYMGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQSFLM 192
            :       ||...:.|...:....:.||::...|..::.|....|:|||||||..|:|...:.::
pombe   134 LFYCISTNVLVSSLLLLGGSQGFSSTTGMNTVAACFLLPLGVMVYTTLGGLKATFISDWIHTVMI 198

  Fly   193 FAAI----YAVIAVSAIKAGGFAAIWDVAVE-------RGRVNFIEFSLDPTVRHTWWSLIIGGM 246
            :..:    |.|...|:: .|..|.::|:..|       .|..:::.|. :..:.:..||::|||:
pombe   199 YIILIVTCYTVYCSSSL-IGSPAKMYDMLKEVQEVYPATGGQSYLSFK-NSEMMYLTWSVMIGGL 261

  Fly   247 VTYLSLYGVNQTQVQRLLSVRNLKSA-QSAL-----WWNLPI-----LGMLSFSTIFSGLSIFYY 300
            .:.....|.:|..:     ..:.||. |..|     ||.:|:     .|:...:.:.:..|:.|
pombe   262 SSVFGDPGYSQRAI-----ASDAKSVFQGYLMGGLCWWIIPMALGSSAGLACRALLLNPASVTY- 320

  Fly   301 YRDCDPLLKGRIDKRDQIMPLFALETM----GQYPGLCGLFVSGIFSASLSTISSAVTSLSAVTL 361
                 |.:...::....:..::.:.::    |...||..||:| |.||:    |:.:.:.|:||.
pombe   321 -----PNVLSSVEISSGLPVIYGMASIFGKSGAAAGLVMLFMS-ITSAT----SAELIAFSSVTT 375

  Fly   362 ED----YLKPLYKAIFKRTLIDSKSTMPTKIVACI-----FGLLCIGLAFVAGSMGGVLQASLTI 417
            .|    |:.|         ..:.|..:.|..::.|     .|.|.:|..: ||...|.|   ||.
pombe   376 YDIFRAYINP---------AANGKQLVRTAHLSVIGFSLFIGALSVGFNY-AGVTAGWL---LTF 427

  Fly   418 FGVVGGPLLAIFTLGVCTTRSNQRGVLLGFLVSLI--VSFWMGFGGPKPKPVTLEFSTAGCENAT 480
            .|::..|.::..||.:...:..:..:::|.....|  |..|:.        .|..|.. |..|..
pombe   428 LGIILTPEVSAVTLCLFWNKMTRFSLVVGAPFGTITGVVCWLA--------STYSFCD-GIVNKD 483

  Fly   481 AVMARAIELSSKSSGVVIEPDYFWLYRISYLW 512
            .||............:...|.|..|  :||:|
pombe   484 TVMTSKACFVGNIVSMASSPLYIVL--LSYIW 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	116/552 (21%)
SPBPB8B6.02c	NP_001018763.1	SLC5sbd_DUR3	11..513	CDD:271370	115/550 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1855
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
TreeFam	0	0.000	Not matched by this tool.
	5	4.860