DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10444 and CG9657

DIOPT Version :9

Sequence 1:	NP_611465.2	Gene:	CG10444 / 37294	FlyBaseID:	FBgn0034494	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster

Alignment Length:	612	Identity:	220/612 - (35%)
Similarity:	331/612 - (54%)	Gaps:	63/612 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 W-DAAVLITILVISALIGIYY----RYTGGKQK---------TTQEYLMADQSMTTFPVSFSLMA 59
            | |..|...:|.|.|:||||:    |....|||         :...||:..:.|..||::.||::
  Fly    15 WPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQMKIFPITMSLIS 79

  Fly    60 SFMSAISLMGVSNESYEFGTIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERRFGQATR 124
            ||:|.|:|:|...|.|.:|..:..|..:.||......|||||||:.:...|.|:|||:|:.::.|
  Fly    80 SFISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQRYNRSLR 144

  Fly   125 LSASLAFTVQMVLYMGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQS 189
            |..|:.|.|..:|::.|.:|.||:|....||::..:...::.:||.||:.:||||||:.|||.|:
  Fly   145 LFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDVIQT 209

  Fly   190 FLMFAAIYAVIAVSAIKAGGFAAIWDVAVERGRVNFIEFSLDPTVRHTWWSLIIGGMVTYLSLYG 254
            .:||.|:..|:....:..||...:|..|.|..|:....||.|.:.|:|::||::||:..:|....
  Fly   210 LIMFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVLGGVAHWLKSNA 274

  Fly   255 VNQTQVQRLLSVRNLKSAQSALWWNLPILGMLSFSTI--FSGLSIFYYYRDCDPLLKGRIDKRDQ 317
            ::|..:||.||:..|:.|:.|:|  ..|.|:|:|..|  ::||.|:..|..||||......:.||
  Fly   275 ISQNMIQRYLSLPTLRDARIAIW--TFIAGVLAFLMICGYTGLLIYATYSQCDPLETKLAQRNDQ 337

  Fly   318 IMPLFALETMGQYPGLCGLFVSGIFSASLSTISSAVTSLSAVTLEDYLKPLYKAIFKRTLIDSKS 382
            ::||..::|:|.||||.|:||:|:|||:||::|:.:.|||||.|||::|...|:    .|.:.::
  Fly   338 LLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKS----PLTEGQT 398

  Fly   383 TMPTKIVACIFGLLCIGLAFVAGSMGGVLQASLTIFGVVGGPLLAIFTLGVCTTRSNQRGVLLGF 447
            ....:.|..:||::.:.|.|....:|.|||.::|:..|..||||.|||.||.....|.:|.|||.
  Fly   399 AFVMRSVVVVFGIIFVALVFAVEKLGAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALLGG 463

  Fly   448 LVSLIVSFWMGFGGP----------KPKPVTLEFSTAGCENATAVMAR---AIELSSKSSGVVIE 499
            ..||||..||.....          |.||    :||.||....|...|   ::.|....|.|...
  Fly   464 FSSLIVMAWMCVSAQRDLVTGDLVYKRKP----YSTMGCNYTFAGEPREFASLALDGAISSVPSA 524

  Fly   500 PDYFWLYRISYLWLSVIGFLIAVVVGYFSSIVLAHCGKAENAEIYLDKSRKQLDYDLFAPMLSRR 564
            |  |.|||||||:.::.|.|:.:||...:|::|        .|..||    .:|..|..|.: ||
  Fly   525 P--FQLYRISYLYFTLFGALVTIVVALVTSLLL--------RETDLD----GVDTRLLTPFV-RR 574

  Fly   565 W---RRHKEE------QDQTAQDETLT 582
            |   |||:..      |..:.:.||.|
  Fly   575 WLERRRHRRSKIPDSGQKSSNKQETKT 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	203/550 (37%)
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	202/549 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448278
Domainoid	1	1.000	233	1.000	Domainoid score	I1353
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1946
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900