Protein Alignment CG10444 and Slc5a1

DIOPT Version :9

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_037165.1
• Gene: Slc5a1 / 25552
• RGDID: 3713
• Length: 665
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 142/679 - (20%)
• Similarity: 265/679 - (39%)
• Gaps: 159/679 - (23%)

  Fly     2 PVGTFD----AWDAAVLITILVISALIGIYYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFM 62
            |:.:::    |.|.:|::...|:...:|::..::..: .|...:.:|.:||..:|:..||.||.:
  Rat    16 PIQSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNR-GTVGGFFLAGRSMVWWPIGASLFASNI 79

  Fly    63 SAISLMGVSNE---------SYEFGTIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERR 118
            .:...:|::..         .:|:..:..|:         :..:.|:|::.:....::.|||.:|
  Rat    80 GSGHFVGLAGTGAAAGIAMGGFEWNALVFVV---------VLGWLFVPIYIKAGVVTMPEYLRKR 135

  Fly   119 FGQATRLSASLAFTVQMVLY----MGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLK 179
            || ..|:...|: .:.::||    :...:::.|:.:....|:...:||.::..:...|:..|||.
  Rat   136 FG-GKRIQIYLS-VLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLA 198

  Fly   180 AVLITDVFQSFLMFAAIYAVIAVSAIKAGGFAAIWD-------VAVERGRVNFIE---------F 228
            ||:.||..|:.:|....:.:...:..:.||:.|..|       ..|..|.:...|         |
  Rat   199 AVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRADSF 263

  Fly   229 SL--DP-TVRHTWWSLIIGGMVTYLSLYGVNQTQVQRLLSVRNLK--SAQSALWWNLPILGMLSF 288
            .:  || |....|..||.|..:..|..:..:|..|||.||.:|:.  .|...|...|.:|.|  |
  Rat   264 HIFRDPITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPM--F 326

  Fly   289 STIFSGLSIFYYYRD---------CDPLLKGRIDKRDQIMPLFALETMGQYPGLCGLFVSGIFSA 344
            ..:..|:.....|.|         |.......:...:...|...:|.|..  ||.||.:|.:.::
  Rat   327 LMVMPGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPN--GLRGLMLSVMMAS 389

  Fly   345 SLSTISSAVTSLSAVTLEDYLKPLYKAIFKRTLIDSKSTMPTKIVACIFGLLCIGLAFV------ 403
            .:|:::|...|.|.:...|....:.|...::.|:         |...:|.|:.||::..
  Rat   390 LMSSLTSIFNSASTLFTMDIYTKIRKGASEKELM---------IAGRLFILVLIGISIAWVPIVQ 445

  Fly   404 AGSMGGVLQASLTIFGVVGGPLLAIFTLGVCTTRSNQRGVLLGFLVSLIVSFWMGFGGPKPKPVT 468
            :...|.:.....:|...:|.|:.|:|.|.:...|.|:.|...|    ||:.|.:|
  Rat   446 SAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWG----LILGFLIG---------- 496

  Fly   469 LEFSTAGCENATAVMARAIELSSKSSGVVIEPDYF--WLYRISYLWLSVIGFLIAVVVGYFSSIV 531
                          ::|.|...:..:|..:||...  .:..:.||:.::|.|.|:||.....|::
  Rat   497 --------------ISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFAISVVTVLVISLL 547

  Fly   532 L-----AH-------------------CGKAENAE------IYLDKSRKQLD-------YDLFAP 559
            .     .|                   .|:.|..|      |.:|....|.:       ||||..
  Rat   548 TKPIPDVHLYRLCWSLRNSTEERIDLDAGEEEPVEEDPKDTIEIDAEAPQKEKGCFRKAYDLFCG 612

  Fly   560 MLSRRWRRHKEEQDQ----TAQDETLTKL 584
            :          :||:    |.::|...||
  Rat   613 L----------DQDKGPKMTKEEEEAMKL 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	123/572 (22%)
Slc5a1	NP_037165.1	SLC5-6-like_sbd	27..665	CDD:382020	140/668 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810