Protein Alignment CG10444 and Slc5a2

DIOPT Version :10

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_573517.1
• Gene: Slc5a2 / 246787
• MGIID: 2181411
• Length: 670
• Species: Mus musculus
• Alignment Length: 622
• Identity: 134/622 - (21%)
• Similarity: 254/622 - (40%)
• Gaps: 129/622 - (20%)

  Fly    17 ILVISA----LIGI----YYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFMSA---ISLMGV 70
            ||||:|    :||:    .:|...|   |...|.:|.:||..:||..||.||.:.:   :.|.|.
Mouse    24 ILVIAAYFLLVIGVGLWSMFRTNRG---TVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLAGT 85

  Fly    71 SNES------YEFGTIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERRF-GQATRLSAS 128
            ...|      :|:..:|.|:         :..:.|:||:......::.:||.:|| |...||..|
Mouse    86 GAASGLAVAGFEWNALFVVL---------LLGWLFVPVYLTAGVITMPQYLRKRFGGHRIRLYLS 141

  Fly   129 LAFTVQMVLY----MGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQS 189
            :   :.:.||    :.:.:::.|:.::...|.:...:::.:..:...|:..|||.|::.||..|:
Mouse   142 V---LSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQT 203

  Fly   190 FLMFAAIYAVIAVSAIKAGGFAAIWDVAVERGRVNFIEFSLDPTVRH------------------ 236
            |::.|..:.:...:..:.||::.::|..:  |.:..:..|.||:|.:
Mouse   204 FVILAGAFILTGYAFHEVGGYSGLFDKYL--GAMTSLTVSKDPSVGNISSTCYQPRPDSYHLLRD 266

  Fly   237 ------TWWSLIIGGMVTYLSLYGVNQTQVQRLLSVRNLK--SAQSALWWNLPILGMLSFSTIFS 293
                  .|.:|::|..:.....:..:|..|||.|:.:||.  .|...|...|.::.|  |..:..
Mouse   267 PVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKNLTHIKAGCILCGYLKLMPM--FLMVMP 329

  Fly   294 GLSIFYYYRD---------CDPLLKGRIDKRDQIMPLFALETMGQYPGLCGLFVSGIFSASLSTI 349
            |:.....|.|         |..:....:...:...|...::.|..  ||.||.::.:.:|.:|::
Mouse   330 GMISRILYPDEVACVVPEVCKRVCGTEVGCSNIAYPRLVVKLMPN--GLRGLMLAVMLAALMSSL 392

  Fly   350 SSAVTSLSAV-TLEDYLKPLYKAIFKRTLIDSKSTMPTKIVACIFGLLCIGLAFVAGSMGGVLQA 413
            :|...|.|.: |::.|.:...:|..|..|:..:..     |..|..:....|..|..:.||.|..
Mouse   393 ASIFNSSSTLFTMDIYTRLRPRAGDKELLLVGRLW-----VVFIVAVSVAWLPVVQAAQGGQLFD 452

  Fly   414 SL-TIFGVVGGPLLAIFTLGVCTTRSNQRGVLLGFLVSLIVSFWMGFGGPKPKPVTLEFSTAGCE 477
            .: ::...:..|:.|:|.|.:...|.|::|...|.:..|:    ||.....|:   ..|.:..|.
Mouse   453 YIQSVSSYLAPPVSAVFVLALFVPRVNEKGAFWGLVGGLL----MGLARLIPE---FFFGSGSCV 510

  Fly   478 NATAVMARAIELSSKSSGVVIEPDYFWLYRISYLWLSVIGFLIAVVVGYFSSIVLAHCGKAENAE 542
            ..:|.                 |..|  .|:.||:.::|.|:.:.::....|:..|...:
Mouse   511 RPSAC-----------------PALF--CRVHYLYFAIILFICSGILTLGISLCTAPIPQ----- 551

  Fly   543 IYLDKSRKQLDYDLFAPMLSRRWRRHKEEQDQTAQDE 579
                |...:|.:.|         |..|||::....||
Mouse   552 ----KHLHRLVFSL---------RHSKEEREDLDADE 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	124/572 (22%)
Slc5a2	NP_573517.1	SLC5-6-like_sbd	22..670	CDD:444915	134/622 (22%)