Protein Alignment CG10444 and Slc5a1

DIOPT Version :9

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_062784.3
• Gene: Slc5a1 / 20537
• MGIID: 107678
• Length: 665
• Species: Mus musculus
• Alignment Length: 670
• Identity: 143/670 - (21%)
• Similarity: 274/670 - (40%)
• Gaps: 141/670 - (21%)

  Fly     2 PVGTFD----AWDAAVLITILVISALIGIYYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFM 62
            |:.:::    |.|.:|::...|:...:|::..::..: .|...:.:|.:||..:|:..||.||.:
Mouse    16 PIPSYERIRNAADISVIVIYFVVVMAVGLWAMFSTNR-GTVGGFFLAGRSMVWWPIGASLFASNI 79

  Fly    63 SAISLMGVSNE---------SYEFGTIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERR 118
            .:...:|::..         .:|:..:..|:         :..:.|:|::.:....::.|||.:|
Mouse    80 GSGHFVGLAGTGAAAGIAMGGFEWNALVLVV---------VLGWIFVPIYIKAGVVTMPEYLRKR 135

  Fly   119 FGQATRLSASLAFTVQMVLY----MGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLK 179
            || ..|:...|: .:.::||    :...:::.|:.:....|:...:||.::..:...|:..|||.
Mouse   136 FG-GKRIQIYLS-VLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGGLA 198

  Fly   180 AVLITDVFQSFLMFAAIYAVIAVSAIKAGGFAAIWD-------VAVERG-----------RVNFI 226
            ||:.||..|:.:|....:.:...:..:.||:.|..|       ..|..|           |.:..
Mouse   199 AVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTPRADSF 263

  Fly   227 EFSLDP-TVRHTWWSLIIGGMVTYLSLYGVNQTQVQRLLSVRNLK--SAQSALWWNLPILGMLSF 288
            ....|| |....|..||.|..:..|..:..:|..|||.||.:|:.  .|...|...|.:|.|  |
Mouse   264 HIFRDPITGDMPWPGLIFGLAILALWYWCTDQVIVQRCLSAKNMSHVKAGCTLCGYLKLLPM--F 326

  Fly   289 STIFSGL--SIFYYYR-------DCDPLLKGRIDKRDQIMPLFALETMGQYPGLCGLFVSGIFSA 344
            ..:..|:  .|.|..:       :|.......:...:...|...:|.|..  ||.||.:|.:.::
Mouse   327 LMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLVVELMPN--GLRGLMLSVMMAS 389

  Fly   345 SLSTISSAVTSLSAV-TLEDYLKPLYKAIFKRTLIDSKSTMPTKIVACIFGLLCIGLAFV----- 403
            .:|:::|...|.|.: |::.|.|...||..|..:|..:          :|.|:.||::..
Mouse   390 LMSSLTSIFNSASTLFTMDIYTKIRKKASEKELMIAGR----------LFILVLIGISIAWVPIV 444

  Fly   404 -AGSMGGVLQASLTIFGVVGGPLLAIFTLGVCTTRSNQRGVLLGFLVSLIVSFWMGFGGPKPKPV 467
             :...|.:.....:|...:|.|:.|:|.|.:...|.|::|...|    ||:.|.:|
Mouse   445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWG----LILGFLIG--------- 496

  Fly   468 TLEFSTAGCENATAVMARAIELSSKSSGVVIEPDYF--WLYRISYLWLSVIGFLIAVVVGYFSSI 530
                           ::|.|...:..:|..:||...  .:..:.||:.::|.|:|:|:.....|.
Mouse   497 ---------------ISRMITEFAYGTGSCMEPSNCPKIICGVHYLYFAIILFVISVITILIISF 546

  Fly   531 VL-----AH----CGKAENAE---IYLD---------KSRKQLDYDLFAPMLSRR-WRRHKE--- 570
            :.     .|    |....|::   |.||         .|:..::.|..||...:. :||..:
Mouse   547 LTKPIPDVHLYRLCWSLRNSKEERIDLDAGEEEDIPEDSKDTIEIDTEAPQKKKGCFRRAYDLFC 611

  Fly   571 --EQDQ----TAQDETLTKL 584
              :||:    |.::|...|:
Mouse   612 GLDQDKGPKMTKEEEEAMKM 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	124/573 (22%)
Slc5a1	NP_062784.3	SLC5-6-like_sbd	27..665	CDD:294310	141/659 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810