Protein Alignment CG10444 and F52H2.4

DIOPT Version :9

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001360058.1
• Gene: F52H2.4 / 186132
• WormBaseID: WBGene00018716
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 166/510 - (32%)
• Similarity: 274/510 - (53%)
• Gaps: 44/510 - (8%)

  Fly    88 YVLSTPIAAYFFLPVFYRMRTTSVYEYLERRFGQATRLSASLAFTVQMVLYMGIALYAPALALEA 152
            ||:|.||.|:.||||.||::.|::|||.||||....|...:..|.|||:||..:|||||:||:.:
 Worm     9 YVISFPIVAFVFLPVLYRLKLTTIYEYFERRFDYKCRFVTTSLFCVQMILYNSVALYAPSLAIAS 73

  Fly   153 VTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQSFLMFAAIYAVIAVSAIKAGGFAAIWDV- 216
            :|.|..:::|::..::..||.::||:||.:.|...|..|:|..:..:|::|..:    .:|.||
 Worm    74 ITNIPITVSILITAVLSAFYISVGGVKAGIHTSAIQMLLIFLTMTFIISISLRE----MSIHDVY 134

  Fly   217 -AVERGRVNFI--EFSLDPTVRHTWWSLIIGGMVTYLSLYGVNQTQVQRLLSVRNLKSAQSALWW 278
             :|..|: .||  :|.::||:||:.|||:|||....|:|:..||..:||.:::..|||||..:..
 Worm   135 TSVVHGK-RFILNDFRINPTIRHSVWSLLIGGTGNILALFAANQLSIQRYMAMDTLKSAQKVVLL 198

  Fly   279 NLPILGMLSFSTIFSGLSIFYYYRDCDPLLKGRIDKRDQIMPLFALETMGQYPGLCGLFVSGIFS 343
            |:....::..|.:..|..|:.:|:||.|    :|...::::|.|.::...:|||..|||.:.::|
 Worm   199 NIVCNTIILVSYVSVGFLIYAHYKDCHP----QIGNANELLPRFVMDVTSKYPGSVGLFAAAVYS 259

  Fly   344 ASLSTISSAVTSLSAVTLEDYLKPLYKAIFKRT-LIDSKSTMPTKIVACIFGLLCIGLAFVAGSM 407
            |.:||:|::.|::|::.:.|..| :|:...|.. |.:.:.....:|:..:...:.|.:||:...:
 Worm   260 AGISTLSASFTAVSSIVINDVWK-VYRERRKMAPLRNDQVQNAMRILPIVLSFISIFVAFLCSML 323

  Fly   408 GG-VLQASLTIFGVVGGPLLAIFTLGVCTTRSNQRGVLLGFLVSLIVSFWMGFGG--PKPKPVTL 469
            .. :||.|..:||..|||:|..|.:|:...|..::..|:|.:.|:||.|.:..|.  .|.|||.|
 Worm   324 QSIILQVSFIVFGAGGGPVLGSFVVGLFVPRVKEKAALVGLIGSIIVCFSISIGSVLVKVKPVAL 388

  Fly   470 EFSTAGCENATAVMARAIELSSKSSGVVIEPDYFWLYR---ISYLWLSVIGFLIAVVVGYFSSIV 531
            |...  |.|.|.....    .|....|...|..|.|.|   |||.:.|:    ||||.....|||
 Worm   389 ELGQ--CSNQTLTYFD----ESFIGAVTSTPLVFGLERIFAISYQYYSI----IAVVTNVALSIV 443

  Fly   532 LAH----CGKAENAEIYLDKSRKQLDYDLFAPMLS-RRWRRHKEEQDQTAQDETL 581
            :..    |.        |..:...:.::|.:|:|: ...:|..|.:....|.:||
 Worm   444 MQKLFELCS--------LTANHLPVSHELVSPLLTYSSSKRDPELEAHRTQRDTL 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	154/453 (34%)
F52H2.4	NP_001360058.1	SLC5-6-like_sbd	1..447	CDD:382020	156/457 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG29060
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		otm14518
orthoMCL	1	0.900	-	-		OOG6_101204
Panther	1	1.100	-	-	LDO	PTHR42985
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6277
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.860