Protein Alignment CG10444 and SLC5A10

DIOPT Version :9

• Sequence 1: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 638
• Identity: 146/638 - (22%)
• Similarity: 246/638 - (38%)
• Gaps: 134/638 - (21%)

  Fly    10 DAAVLITILVISALIGIYYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFMSAISLMGVSNES 74
            |..|:.....::..:||:......: .|...|.:|.:.||.:|:..||.||...:...:|::...
Human    20 DIIVITVYFALNVAVGIWSSCRASR-NTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSG 83

  Fly    75 YEFGTIFCVI--NIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERRF-GQATRLSAS-LAFTVQM 135
            ...|......  |..|||..  .|:.|:|::......::.||:::|: ||..|:..| |:..:.:
Human    84 AAGGLAVAGFEWNATYVLLA--LAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSV 146

  Fly   136 VLYMGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQSFLMFAAIYAVI 200
            ...:.:.|||.||.:....|.:..::.::...:...|:..|||.||:.||..|:.:|  .:.|||
Human   147 FTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIM--VVGAVI 209

  Fly   201 AVSAIKA----GGFA-------------AIWDVAVERGRVNFIEFSLDPTVRHT----WWSLIIG 244
            .  .|||    ||:.             .|.:......|.:.:....||   ||    |..:..|
Human   210 L--TIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDP---HTGDLPWTGMTFG 269

  Fly   245 GMVTYLSLYGVNQTQVQRLLSVRNLKSAQSA---------LWWNLPIL-GMLSFSTIFSGLSIFY 299
            ..:.....:..:|..|||.||.|:|..|::.         |...|.|: ||:| ..:|.|..:
Human   270 LTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLIIMPGMIS-RALFPGAHV-- 331

  Fly   300 YYRDCDPLLKGRIDKRDQIMPLFALETMG--------QYP---------GLCGLFVSGIFSASLS 347
             |.:...:...|.|....::|...|...|        .||         ||.||.::.:.:|.:|
Human   332 -YEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMS 395

  Fly   348 TISSAVTSLSAVTLEDYLKPLYKAIFKRTLI-----DSKSTMPT-------------KIVACIFG 394
            :::|...|.|.:...|..:.|.....:|.|:     ...||.|.             .:...:.|
Human   396 SLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRTGIPSTPPAPQSRLSFLLPETPPLERYLLG 460

  Fly   395 LLCIGLAFVAGSMGG-------VLQAS---------LTIFGVVGGPLLAIFTLGVCTTRSNQRGV 443
            |:.:.|..|..::.|       |||.|         .::...:..|:.|:|.|||...|:|::|.
Human   461 LVVMDLWLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGA 525

  Fly   444 LLGFLVSLIVS---FWMGFGGPKP---KPVT----------LEFSTAGCENATAVMARAIELSSK 492
            ..|.:..|:|.   ..:.|..|.|   :|.|          |.|:.|....:.||:.....|:..
Human   526 FWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPP 590

  Fly   493 SSGVVIEPDYFWLY----------------RISYLWLSVIGF--LIAVVVGYF 527
            ...|.||...:|..                :....|..|.||  ::.:.|..|
Human   591 PQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILLMCVNIF 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	146/638 (23%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:320982	146/638 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810