Protein Alignment PCNA and PCNA

DIOPT Version :9

• Sequence 1: NP_476905.1
• Gene: PCNA / 37290
• FlyBaseID: FBgn0005655
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_002583.1
• Gene: PCNA / 5111
• HGNCID: 8729
• Length: 261
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 184/259 - (71%)
• Similarity: 223/259 - (86%)
• Gaps: 0/259 - (0%)

  Fly     1 MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKFRCDRN 65
            ||||||.|.:||||:|:|:|||:|||.:|.|.||:.||:||:||||||.|||||:|||.:|||||
Human     1 MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRN 65

  Fly    66 LSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMNLDQEHLGIPE 130
            |:||:||.||:||||||.|||.:|::|:|||||:.::||:.|||||||||||||:||.|.|||||
Human    66 LAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPE 130

  Fly   131 TDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANIKLAQTGSVDKEEEAV 195
            .::||||:||:.|||||||||:...::|||.|.|:||||||||::|..||||:||.:||||||||
Human   131 QEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAV 195

  Fly   196 IIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYAIKDLGHIRYYLAPKIEDNE 259
            .|||.|||.||||.||||.||||||||:.|.|||.|||||||||.|.|:||::|||||||||.|
Human   196 TIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEE 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PCNA	NP_476905.1	pcna	1..259	CDD:273158	183/257 (71%)
PCNA	NP_002583.1	pcna	1..259	CDD:273158	183/257 (71%)
		Interaction with NUDT15. /evidence=ECO:0000269|PubMed:19419956	7..100		63/92 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159145
Domainoid	1	1.000	191	1.000	Domainoid score	I3255
eggNOG	1	0.900	-	-		E1_COG0592
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1945
Inparanoid	1	1.050	379	1.000	Inparanoid score	I2077
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62193
OrthoDB	1	1.010	-	-		D1012066at2759
OrthoFinder	1	1.000	-	-		FOG0003572
OrthoInspector	1	1.000	-	-		oto89221
orthoMCL	1	0.900	-	-		OOG6_100882
Panther	1	1.100	-	-	LDO	PTHR11352
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2713
SonicParanoid	1	1.000	-	-		X2443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800