DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PCNA and pcna

DIOPT Version :9

Sequence 1:	NP_476905.1	Gene:	PCNA / 37290	FlyBaseID:	FBgn0005655	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_571479.2	Gene:	pcna / 30678	ZFINID:	ZDB-GENE-000210-8	Length:	260	Species:	Danio rerio

Alignment Length:	260	Identity:	178/260 - (68%)
Similarity:	220/260 - (84%)	Gaps:	0/260 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKFRCDRN 65
            ||||||.|.:||||:|:|:|||:.||.:|.|.|||.||:||:||||||.|||||||||.:|||||
Zfish     1 MFEARLVQGSILKKVLEALKDLITEACWDVSSSGISLQSMDSSHVSLVQLTLRSDGFDSYRCDRN 65

  Fly    66 LSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMNLDQEHLGIPE 130
            |:||:||.||:||||||.|||.:|::|:||||.:.::||:.|||||||||||||:||.|.|||||
Zfish    66 LAMGVNLSSMSKILKCAGNEDIITLRAEDNADALALVFETLNQEKVSDYEMKLMDLDVEQLGIPE 130

  Fly   131 TDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANIKLAQTGSVDKEEEAV 195
            .::||||:||:.|||||||||:|..::|:|.|.|:||||||||::||.||||:||.:||||:|||
Zfish   131 QEYSCVVKMPSGEFARICRDLSQIGDAVMISCAKDGVKFSASGELGTGNIKLSQTSNVDKEDEAV 195

  Fly   196 IIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYAIKDLGHIRYYLAPKIEDNET 260
            .|||.|||.|.||..|||.||||||||..|.|||.||:||||||.|.|:||::|||||||::..:
Zfish   196 TIEMNEPVQLIFALNYLNFFTKATPLSKTVTLSMSADIPLVVEYKIADMGHVKYYLAPKIDEESS 260

Fly 261 260
Zfish 261 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PCNA	NP_476905.1	pcna	1..259	CDD:273158	178/257 (69%)
pcna	NP_571479.2	pcna	1..258	CDD:273158	178/256 (70%)
pcna	NP_571479.2	PCNA	4..256	CDD:238322	174/251 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595211
Domainoid	1	1.000	187	1.000	Domainoid score	I3273
eggNOG	1	0.900	-	-		E1_COG0592
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1945
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2088
OMA	1	1.010	-	-		QHG62193
OrthoDB	1	1.010	-	-		D1012066at2759
OrthoFinder	1	1.000	-	-		FOG0003572
OrthoInspector	1	1.000	-	-		oto40616
orthoMCL	1	0.900	-	-		OOG6_100882
Panther	1	1.100	-	-	LDO	PTHR11352
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2713
SonicParanoid	1	1.000	-	-		X2443
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	18	18.300