DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsl and CXE18

DIOPT Version :9

Sequence 1:	NP_611463.1	Gene:	Hsl / 37289	FlyBaseID:	FBgn0034491	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_197744.1	Gene:	CXE18 / 832418	AraportID:	AT5G23530	Length:	335	Species:	Arabidopsis thaliana

Alignment Length:	208	Identity:	53/208 - (25%)
Similarity:	87/208 - (41%)	Gaps:	40/208 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 PAEPLKLPRRKNFKASDNLSSDVNQNQGDG----------DFVEIPVPTAHLGPGLPVSVRLLSA 369
            |.:.|.||.:.....:...:...|..:.||          ||         ..|..|..|.::|.
plant     7 PNQKLTLPLKTRIALTVISTMTDNAQRPDGTINRRFLRLFDF---------RAPPNPKPVNIVST 62

  Fly   370 RRRSGMLGEGRYRGWHKPIPPS------PSILFHCHGGG--FVAQSSKSHELYLRDWAVALDCPI 426
               |..:.:.....|.:...|.      |.::|. ||||  |::.::..::...|.:|..|...:
plant    63 ---SDFVVDQSRDLWFRLYTPHVSGDKIPVVVFF-HGGGFAFLSPNAYPYDNVCRRFARKLPAYV 123

  Fly   427 LSVDYSLAPEAPFPRALQEVYYAYCWL-LNNTELLGTTAERVVC--AGDSAGANLSIGVALK-CI 487
            :||:|.||||..:|....:.:.|..:: .|:..:|...|:...|  ||||||.|::..||:: |
plant   124 ISVNYRLAPEHRYPAQYDDGFDALKYIEENHGSILPANADLSRCFFAGDSAGGNIAHNVAIRIC- 187

  Fly   488 EQGVRVPDGLFLA 500
                |.|...|.|
plant   188 ----REPRSSFTA 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	14/70 (20%)
		Aes	350..>537	CDD:223730	44/163 (27%)
		Abhydrolase	395..>539	CDD:304388	36/112 (32%)
		Abhydrolase	<767..827	CDD:304388
CXE18	NP_197744.1	Abhydrolase_3	90..307	CDD:369561	36/113 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263520at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820