DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsl and Afmid

DIOPT Version :9

Sequence 1:	NP_611463.1	Gene:	Hsl / 37289	FlyBaseID:	FBgn0034491	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	XP_017453019.1	Gene:	Afmid / 688283	RGDID:	1591143	Length:	312	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	71/373 - (19%)
Similarity:	119/373 - (31%)	Gaps:	124/373 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 WFLAESEMMHKLPS------------IVGSSIKVNRLIELPAEPLKLPRRKNFKASDNLSSDVNQ 339
            |....||.:.|..|            :||:.:::.   ....:..:..||...        ||:.
  Rat    14 WRTLSSEELEKQYSPRRWVIRMKTEEVVGNFMQIG---SQATQKARATRRNQL--------DVSY 67

  Fly   340 NQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGMLGEGRYRGWHKPIPPSPSILFHCHGGGFV 404
            ..|.|:.::|..|...                             .|..|     ||....||:.
  Rat    68 GDGVGEKMDIYFPDED-----------------------------SKAFP-----LFMFLHGGYW 98

  Fly   405 AQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLNNTELLGTTAERVVC 469
            ...||....::.:...|....:..|.|.:||:....:.:.:|..:..:|....    .:.|.:..
  Rat    99 QSGSKDDSAFMVNPLTAQGIVVAVVAYDIAPKGTLDQMVDQVSRSVVFLQRRY----PSNEGIYL 159

  Fly   470 AGDSAGANLSIGVAL-KCIEQGVRVPD--GLFLAYCPTLVSFVPSPARLLCLMDPLLPFGFMMRC 531
            .|.||||:|:..:.| ...:.|| .|:  ||.      |||.:..       ::||:
  Rat   160 CGHSAGAHLAAMMLLASWTKHGV-TPNIQGLL------LVSGIYD-------LEPLV-------- 202

  Fly   532 LRAYAAPAQETLQQNAKQVEDAAQIRNVPKSNVGSLNSSRRTSMARS--PLSPLEASMNPDDESS 594
                 ..:|..|..  ..:|||.  ||.|:..:       ..:.||.  |..|:...:...|
  Rat   203 -----FTSQNDLLH--MTLEDAE--RNSPQRLL-------EVAPARPVVPAYPVLVFVAQHD--- 248

  Fly   595 DTFASASASYHSQTVERTDLPHTEGDNSSCVSFEDDSQPIVHYPIEIS 642
                  |..:|.|:.|..::|.|           ....|:.|..|.:|
  Rat   249 ------SPEFHRQSKEFCEVPPT-----------TSLAPVQHRVISLS 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	15/100 (15%)
		Aes	350..>537	CDD:223730	34/189 (18%)
		Abhydrolase	395..>539	CDD:304388	31/146 (21%)
		Abhydrolase	<767..827	CDD:304388
Afmid	XP_017453019.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900