Protein Alignment Hsl and Aadacl2

DIOPT Version :9

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001121563.1
• Gene: Aadacl2 / 639634
• MGIID: 3646333
• Length: 401
• Species: Mus musculus
• Alignment Length: 536
• Identity: 108/536 - (20%)
• Similarity: 170/536 - (31%)
• Gaps: 213/536 - (39%)

  Fly   307 KVNRLIELPAEPLKLPRRKNF-KASDNLS-----SDVNQNQGDGDFVEIPVPTAHLGPGLPVSVR 365
            |...|:.|..|.|.:.|.:.| ....||.     ||.:....|..||:||             ||
Mouse    41 KTCSLMALCLENLGVMRYEEFISMIINLDYTQPLSDEHITVTDTAFVDIP-------------VR 92

  Fly   366 LLSARRRSGMLGEGRYRGWHKPIPPSPSILFHCHGGGFVAQSSKSHEL-YLRDW-AVALDCPILS 428
            |...:|:|.              .|..::::. |||||...|.|.... :|..| |..||..::.
Mouse    93 LYLPKRKSE--------------APRRAVIYF-HGGGFCFGSFKQRAFDFLNRWTANKLDAVVVG 142

  Fly   429 VDYSLAPEAPFPRALQEVYYAYCWLLNNTEL--LGTTAERVVCAGDSAGANLSIGVALKCIEQGV 491
            :||.|||:..||...::...|..:.|.:..|  .|....|:..:|||:|..|:..|
Mouse   143 IDYRLAPQHHFPAQFEDGITAVKFFLQDKILTKYGVDPTRIAVSGDSSGGTLAAAV--------- 198

  Fly   492 RVPDGLFLAYCPTLVSFVPSPARLLCLMDPLLPFGFMMRCLRAYAAPAQETLQQNAKQVEDAAQI 556
                                                                   .:||:...::
Mouse   199 -------------------------------------------------------TQQVQIDPEV 208

  Fly   557 RNVPKSNVGSLNSSRRTSMARSPLSPLEASMNPDDESSDTFASASASYHSQTVERTDLP-HTEGD 620
            ::..|                     |:|.:.|..:..|                |.|| |.|.:
Mouse   209 KHKLK---------------------LQALLYPGLQVID----------------THLPSHRENE 236

  Fly   621 NSSCVSFEDDSQPIVHYPIEISADPPKDTASAAYIDNFLDKYLIDTATMEVTEETAPEAVQAQAN 685
            :.                |.::.|     .:...:..|..|           :|..|:|:  :.|
Mouse   237 HG----------------IVLTRD-----IAIKLVSLFFTK-----------DEALPQAM--RKN 267

  Fly   686 GHAKISSDDDILVETGRDLVAIDTLQGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDA 750
            .|....|         |.|.              ...|..|.....:         ::|....:.
Mouse   268 QHMPPES---------RHLF--------------RFVNWSTLLPDKF---------RKDHVYTEP 300

  Fly   751 LIARSPSEEFAFDVP--KDPFLSPYWASDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQ 813
            ::.||     ||.:|  .|....|..|||:.|..||:|.|||...|...||.:|:..:|:::|.|
Mouse   301 VLGRS-----AFSLPALMDHRALPLLASDDHLQHLPQTYILTCQHDVLRDDGIMYVSRLQKVGVQ 360

  Fly   814 VDLEILEGLPHGFLNF 829
            |..:.:|...||.|::
Mouse   361 VFHDHVEDGIHGALSY 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	21/74 (28%)
		Aes	350..>537	CDD:223730	37/190 (19%)
		Abhydrolase	395..>539	CDD:304388	30/147 (20%)
		Abhydrolase	<767..827	CDD:304388	23/59 (39%)
Aadacl2	NP_001121563.1	Aes	75..372	CDD:223730	96/496 (19%)
		Abhydrolase_3	107..372	CDD:285143	83/437 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263520at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820