Protein Alignment Hsl and Aadacl2

DIOPT Version :10

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001121563.1
• Gene: Aadacl2 / 639634
• MGIID: 3646333
• Length: 401
• Species: Mus musculus
• Alignment Length: 536
• Identity: 108/536 - (20%)
• Similarity: 170/536 - (31%)
• Gaps: 213/536 - (39%)

  Fly   307 KVNRLIELPAEPLKLPRRKNF-KASDNLS-----SDVNQNQGDGDFVEIPVPTAHLGPGLPVSVR 365
            |...|:.|..|.|.:.|.:.| ....||.     ||.:....|..||:||             ||
Mouse    41 KTCSLMALCLENLGVMRYEEFISMIINLDYTQPLSDEHITVTDTAFVDIP-------------VR 92

  Fly   366 LLSARRRSGMLGEGRYRGWHKPIPPSPSILFHCHGGGFVAQSSKSHEL-YLRDW-AVALDCPILS 428
            |...:|:|.              .|..::::. |||||...|.|.... :|..| |..||..::.
Mouse    93 LYLPKRKSE--------------APRRAVIYF-HGGGFCFGSFKQRAFDFLNRWTANKLDAVVVG 142

  Fly   429 VDYSLAPEAPFPRALQEVYYAYCWLLNNTEL--LGTTAERVVCAGDSAGANLSIGVALKCIEQGV 491
            :||.|||:..||...::...|..:.|.:..|  .|....|:..:|||:|..|:..|
Mouse   143 IDYRLAPQHHFPAQFEDGITAVKFFLQDKILTKYGVDPTRIAVSGDSSGGTLAAAV--------- 198

  Fly   492 RVPDGLFLAYCPTLVSFVPSPARLLCLMDPLLPFGFMMRCLRAYAAPAQETLQQNAKQVEDAAQI 556
                                                                   .:||:...::
Mouse   199 -------------------------------------------------------TQQVQIDPEV 208

  Fly   557 RNVPKSNVGSLNSSRRTSMARSPLSPLEASMNPDDESSDTFASASASYHSQTVERTDLP-HTEGD 620
            ::..|                     |:|.:.|..:..|                |.|| |.|.:
Mouse   209 KHKLK---------------------LQALLYPGLQVID----------------THLPSHRENE 236

  Fly   621 NSSCVSFEDDSQPIVHYPIEISADPPKDTASAAYIDNFLDKYLIDTATMEVTEETAPEAVQAQAN 685
            :.                |.::.|     .:...:..|..|           :|..|:|:  :.|
Mouse   237 HG----------------IVLTRD-----IAIKLVSLFFTK-----------DEALPQAM--RKN 267

  Fly   686 GHAKISSDDDILVETGRDLVAIDTLQGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDA 750
            .|....|         |.|.              ...|..|.....:         ::|....:.
Mouse   268 QHMPPES---------RHLF--------------RFVNWSTLLPDKF---------RKDHVYTEP 300

  Fly   751 LIARSPSEEFAFDVP--KDPFLSPYWASDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQ 813
            ::.||     ||.:|  .|....|..|||:.|..||:|.|||...|...||.:|:..:|:::|.|
Mouse   301 VLGRS-----AFSLPALMDHRALPLLASDDHLQHLPQTYILTCQHDVLRDDGIMYVSRLQKVGVQ 360

  Fly   814 VDLEILEGLPHGFLNF 829
            |..:.:|...||.|::
Mouse   361 VFHDHVEDGIHGALSY 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:461882	21/74 (28%)
		alpha/beta hydrolases	395..>539	CDD:473884	30/147 (20%)
		Aes	<767..838	CDD:440422	24/63 (38%)
Aadacl2	NP_001121563.1	Abhydrolase_3	107..372	CDD:400284	83/437 (19%)