Protein Alignment Hsl and Aadacl4fm2

DIOPT Version :9

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001079011.1
• Gene: Aadacl4fm2 / 627085
• MGIID: 3652194
• Length: 406
• Species: Mus musculus
• Alignment Length: 601
• Identity: 109/601 - (18%)
• Similarity: 165/601 - (27%)
• Gaps: 251/601 - (41%)

  Fly   285 SFWFLAESEMMHKLPSIVGSSIKVNRL-------IEL--PAEPLKL-PRRKNFKASDNLSSDVNQ 339
            |.|.|.:..:...:|..:...:|.:.|       |.|  ..|.:|: |..:.|....:|....|
Mouse    19 SVWVLIKEILTVHVPPPIPQRVKFHMLHYFFQLTIALGNVLEKMKICPMPRFFCFIQDLLVSKN- 82

  Fly   340 NQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGMLGEGRYRGWHKPIPPSPSILFHCHGGGFV 404
            |.|      :.|...|.|   .:.|||...:..|.              .|...|:|: ||||.|
Mouse    83 NFG------VLVKNMHFG---TIPVRLFQPKATSS--------------GPRKGIIFY-HGGGGV 123

  Fly   405 AQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLNNTELLGTTAERVVC 469
            ..|..|:.......|...|..:::|.|...|:...|.|..:...|....|...:..|....|||.
Mouse   124 FGSLDSYHNTCSYLAHETDSVVMAVGYRKLPDHHHPTAYHDCLNATVHFLKELKTYGVDPARVVV 188

  Fly   470 AGDSAGANLSIGVA-----------------LKCIEQGVRVPDGLFLAYCPTLVSFVPSPARLLC 517
            :|:|.||..:..:|                 :..:.|||......:..|...
Mouse   189 SGESIGAGAAAIIAQVVLARKDLPQFRAQVLINPVVQGVNFQLPSYQQYSDV------------- 240

  Fly   518 LMDPLLPFGFMMRCLRAYAAPAQETLQQNAKQVEDAAQIRNVPKSNVGSLNSSRRTSMARSPLSP 582
               |.|...|:|.|...|.|                             ::.|.:.:|.:....|
Mouse   241 ---PFLSRKFLMTCACKYLA-----------------------------IDQSWKDAMLKGTFIP 273

  Fly   583 LEASMNPDDESSDTFASASASYHSQTVERTDLPHTEGDNSSCVSFEDDSQPIVHYPIEISADPPK 647
                  ||                                             |:
Mouse   274 ------PD---------------------------------------------HW---------- 277

  Fly   648 DTASAAYIDNFLDKYLIDTATMEVTEETAPEAVQAQANGHAKISSDDDI---LVETGRDLVAIDT 709
                        .||                         ||..|.|:|   ....||.    ..
Mouse   278 ------------KKY-------------------------AKWLSSDNIPQRFKSQGRQ----PE 301

  Fly   710 LQGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDALIARSPSEEFAFDVPKDPFLSPYW 774
            ..|...|:....||.:                                  |:.:.      ||..
Mouse   302 FPGPFNESAYLETNHI----------------------------------FSLET------SPLL 326

  Fly   775 ASDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQVDLEILEGLPHG--------FLNFTM 831
            |.|:.::|||||.:::...|...||.:::.|:|:..|..|....||...||        .|:|.
Mouse   327 ADDKIIAQLPETFLVSSEYDVLRDDTLLYKKRLEEQGVPVTWCHLEDGFHGCIVLFDKNALSFP- 390

  Fly   832 LSNEAMEGSKKCIKSL 847
            .|.:||..:...||.:
Mouse   391 CSKKAMSSTVSFIKGI 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	23/100 (23%)
		Aes	350..>537	CDD:223730	45/203 (22%)
		Abhydrolase	395..>539	CDD:304388	37/160 (23%)
		Abhydrolase	<767..827	CDD:304388	20/67 (30%)
Aadacl4fm2	NP_001079011.1	Aes	<96..404	CDD:223730	88/510 (17%)
		Abhydrolase	114..379	CDD:304388	78/452 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263520at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820