Protein Alignment Hsl and Aadac

DIOPT Version :9

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_065413.1
• Gene: Aadac / 57300
• RGDID: 631440
• Length: 398
• Species: Rattus norvegicus
• Alignment Length: 503
• Identity: 99/503 - (19%)
• Similarity: 150/503 - (29%)
• Gaps: 209/503 - (41%)

  Fly   334 SSDVNQNQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGMLGEGRYRGWHKPIPPSPSILFHC 398
            :||.|....:.||..:|             ||:...:|:|..|..|               ||..
  Rat    73 TSDENVTVMETDFNSVP-------------VRIYIPKRKSTTLRRG---------------LFFI 109

  Fly   399 HGGGFVAQSSK--SHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLNN--TEL 459
            ||||:...|:.  .::...|..|..||..::|.||.|||:..||:..::||::..|.|..  .|.
  Rat   110 HGGGWCLGSAAYFMYDTLSRRTAHRLDAVVVSTDYGLAPKYHFPKQFEDVYHSLRWFLQEDILEK 174

  Fly   460 LGTTAERVVCAGDSAGANLSIGVALKCIEQGVRVPDGLFLAYCPTLVSFVPSPARLLCLMDPLLP 524
            .|....||..:|||||.||:..|..:                               .|.||.:.
  Rat   175 YGVDPRRVGVSGDSAGGNLTAAVTQQ-------------------------------ILQDPDVK 208

  Fly   525 FGFMMRCLRAYAAPAQETLQQNAKQVEDAAQIRNVPKSNVGSLNSSRRTSMARSPLSPLEASMNP 589
            ....::.|   ..||.:.|..            |||
  Rat   209 IKLKVQAL---IYPALQALDM------------NVP----------------------------- 229

  Fly   590 DDESSDTFASASASYHSQTVERTDLPHTEGDNSSCVSFEDDSQPIVHYPIEISADPPKDTASAAY 654
                                                |.:::||    ||:          .:.:.
  Rat   230 ------------------------------------SQQENSQ----YPL----------LTRSL 244

  Fly   655 IDNFLDKYLIDTATMEVTEETAPEAVQAQANGHAKISSDDDILVETGRDLVAIDTLQGRLQEAVN 719
            :..|..:|.                                   .|.|||.....|...:....:
  Rat   245 LIRFWSEYF-----------------------------------TTDRDLEKAMLLNQHVPVEFS 274

  Fly   720 NITNTLTRCTQSYEIHGSNVMAQQDVRNMDALIARSP---SEEFAFDVP--KDPFLSPYWASDEW 779
            ::...         ::.|:::.|   |.......::|   |.|.|...|  .|....|..|:|..
  Rat   275 HLLQF---------VNWSSLLPQ---RYKKGYFYKTPTPGSLELAQKYPGFTDVKACPLLANDSI 327

  Fly   780 LSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQVDLEILEGLPHGFL 827
            |..||.|.|:|...|...||.:|:.|:|:..|..|....:|...||.|
  Rat   328 LHHLPMTYIITCQYDVLRDDGLMYVKRLQNTGVHVTHHHIEDGFHGAL 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	10/41 (24%)
		Aes	350..>537	CDD:223730	46/190 (24%)
		Abhydrolase	395..>539	CDD:304388	39/147 (27%)
		Abhydrolase	<767..827	CDD:304388	21/59 (36%)
Aadac	NP_065413.1	Aes	<88..373	CDD:223730	91/484 (19%)
		Abhydrolase_3	106..373	CDD:285143	84/438 (19%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	110..112		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263520at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820