Protein Alignment Hsl and lipea

DIOPT Version :10

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001303654.1
• Gene: lipea / 568368
• ZFINID: ZDB-GENE-060503-734
• Length: 696
• Species: Danio rerio
• Alignment Length: 865
• Identity: 276/865 - (31%)
• Similarity: 406/865 - (46%)
• Gaps: 204/865 - (23%)

  Fly    40 HQHVPADLEA----TYGTLYAACQDHAAFFARDHTEFGQRLHAAHIAWQDFIVLANRLVQQIDAF 100
            |:||.|.|:.    ...||..:..:.:      :.:..:||.......|:.......|:......
Zfish     3 HKHVFAGLQTICLDVISTLNGSSSNSS------NADAAERLLGVMKQIQEHGRAVEPLITGFMTV 61

  Fly   101 AHEYDFDEQTPGNGYRSFIYVTNACIAHGISICQQLTATRSTIFFRKKFYMKEVEA-CSQLLSSL 164
            .|.:|.||||||||||:.:.|.::||.|.....:.:.:..:..|||....:.|:|| |    |:|
Zfish    62 YHHFDLDEQTPGNGYRTLVKVVHSCIIHITHKARYIASNCTGAFFRMDHNVAEMEAYC----SAL 122

  Fly   165 CTCLQYLLILRQ-----------WSASTGDLFACGNHTAEQLFELGDTINQYCFYGRCLGFQYGD 218
            |. |:.||.|.|           :|...|.|       :|:..:...::::.||||||||||:..
Zfish   123 CQ-LRALLYLAQVLLNDNPNGQLYSQEEGGL-------SERFVQEYISMHKACFYGRCLGFQFSP 179

  Fly   219 SIRGVLRFLGISMASYSESYYSQEGDGPIVKTTRSLWTSGKYLMNPELRARRIVNISQNAKIDFC 283
            |:|..|:.:.|||.|:.|:|..|:....|  ...|.:|||||:::||||......|:||..:.|.
Zfish   180 SLRPFLQTVVISMVSFGENYKKQQTGLGI--AALSFFTSGKYVVDPELRGAEFERITQNLDMQFW 242

  Fly   284 KSFWFLAESEMMHKLPSIVGSSIKVNRLIELPAEPLKLPRRKNFKASDNLSSDVNQNQGDGDFVE 348
            |:||.:.|:|::..|..|..|.::||..:.:|||.|.||          |:||.:.:      |.
Zfish   243 KTFWNITETELLSGLTRITSSVVQVNVTLTVPAESLSLP----------LASDPSLS------VA 291

  Fly   349 IPVPTAHLGPGLPVSVRLLSARRRSG-----MLGEGRYRG---------WHKPIPPSPSILFHCH 399
            :..|.||.||| ||:|||:|...|.|     :|...|..|         ..:..|.||.:|.|.|
Zfish   292 VKPPVAHWGPG-PVNVRLISHVLRQGQDSAELLSLSRPEGPQLSLSGGFNRQTAPLSPCLLIHFH 355

  Fly   400 GGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLNNTELLGTTA 464
            |||||||:|||||.||:.|:..|:.|||||||||||||||||||:|.:|||||.|.|..|||:||
Zfish   356 GGGFVAQTSKSHENYLKSWSKDLNVPILSVDYSLAPEAPFPRALEECFYAYCWALKNCHLLGSTA 420

  Fly   465 ERVVCAGDSAGANLSIGVALKCIEQGVRVPDGLFLAYCPTLVSFVPSPARLLCLMDPLLPFGFMM 529
            |.|...|||||.||.|.|:::.:..|||||||:..||..||::...||:|||.|:|||||...:.
Zfish   421 EHVCLVGDSAGGNLCITVSMRAMSHGVRVPDGIVAAYPATLLTTDASPSRLLTLIDPLLPLSVLY 485

  Fly   530 RCLRAYAAPAQETLQQNAKQVEDAAQIRNVPKSNVGSLNSSRRTSMARSPLSPLEASMNPD-DES 593
            :|:.|||..:..::|. |:|::..|.:        |.......:..|:...:.::..::|. ..|
Zfish   486 KCIDAYAGLSCRSVQP-AQQLDTLAAL--------GQDTVKMLSKFAQGATNWIQTLLDPKAPPS 541

  Fly   594 SDTFASASASYHSQTVERTDLPHTEGDNSSCVSFEDDSQPIVHYPIEISADPPKDTASAAYIDNF 658
            |.:.|||:.|.:..:..:   ||:          |:..|.:..||                 :||
Zfish   542 SSSTASATTSSNGPSSFK---PHS----------EEAPQEVKEYP-----------------ENF 576

  Fly   659 LDKYLIDTATMEVTEETAPEAVQAQANGHAKISSDDDILVETGRDLVAIDTLQGRLQEAVNNITN 723
                               |.:::..                                    :.:
Zfish   577 -------------------EPLRSSC------------------------------------LVD 586

  Fly   724 TLTRCTQSYEIHGSNVMAQQDVRNMDALIARSPSEEFAFDVPKDPFLSPYWASDEWLSQLPETKI 788
            ..|.||                                 .:.|:||:||..|.|..|..||...|
Zfish   587 IKTPCT---------------------------------PIMKNPFVSPLLAPDSLLKGLPPVHI 618

  Fly   789 LTLNMDPCLDDCVMFAKKLKRLGRQVDLEILEGLPHGFLNFTMLSNEAMEGSKKCIKSLQTLLQT 853
            :...:|..|||.|||||||:.:.:.|.|.::|.||||||:...||.|..|.:..|:|.::.:|:.
Zfish   619 VASALDALLDDSVMFAKKLRNMNQPVTLTVVEDLPHGFLSLLQLSKETQEAADICVKRIREVLKL 683

  Fly   854 DSKTKNIDKANSMDEEESSS 873
            :..|         |:::.||
Zfish   684 EEPT---------DDQKQSS 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:461882	110/341 (32%)
		alpha/beta hydrolases	395..>539	CDD:473884	88/143 (62%)
		Aes	<767..838	CDD:440422	33/70 (47%)
lipea	NP_001303654.1	HSL_N	6..318	CDD:461882	113/348 (32%)
		Abhydrolase_3	351..657	CDD:400284	142/432 (33%)