Protein Alignment Hsl and RGD1563334

DIOPT Version :9

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: XP_578509.2
• Gene: RGD1563334 / 502999
• RGDID: 1563334
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 115/611 - (18%)
• Similarity: 173/611 - (28%)
• Gaps: 269/611 - (44%)

  Fly   285 SFWFLAESEMMHKLPSIVGSSIKVNRL-------IEL--PAEPLKL---PRRKNFKASDNLSSDV 337
            |.|.|.:.....::|..:...:|.:.|       |.|  ..|.:||   ||...| ..|.|.|
  Rat    19 SVWVLIKEIFTVRVPPPIRQRVKFHILHYFFQLTIALGNVLEKMKLCSMPRFFCF-LQDLLVS-- 80

  Fly   338 NQNQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGMLGEGRYRGWHKPIPPSPSILFHCHGGG 402
            ..|.|      :.|...|.|   .:.|||...:..|    .|..||          |:|: ||||
  Rat    81 KNNFG------VLVKNLHFG---TIPVRLFQPKTTS----SGPRRG----------IIFY-HGGG 121

  Fly   403 FVAQSSKS-HEL--YLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLNNTELLGTTA 464
            .:...... |.|  ||   |...|..:|||.|...|:...|...|:...|....|...:..|...
  Rat   122 CMFGGLDCYHNLCSYL---ASETDSVLLSVGYRKLPDHHHPIVYQDCLNATIHFLKELKTYGIDP 183

  Fly   465 ERVVCAGDSAGANLSIGVALKCIE-----------------QGVRVPDGLFLAYCPTLVSFVPSP 512
            |:||.:|:|.||..:..:|...::                 ||:..          .|.|:...|
  Rat   184 EQVVISGESIGAGAAAIIAQALLDRKDLPKFRAQVLINPVIQGINF----------QLPSYQQYP 238

  Fly   513 ARLLCLMDPLLPFGFMMRCLRAYAAPAQETLQQNAKQVEDAAQIRNVPKSN-------VGSLNSS 570
            ..      |.|...|::.|:..|       |..:...::|..:...:|..|       :.|.|..
  Rat   239 NA------PFLSRKFLVTCVCKY-------LAIDLSWMDDMLKGTFIPPDNWKKYKKWLSSDNIP 290

  Fly   571 RRTSMARSPLSPLEASMNPDDESSDTFASASASYHSQTVERTDLPHTEGDNSSCVSFEDDSQPIV 635
            :|..           |..|..||...|
  Rat   291 QRFK-----------SQGPQPESPGPF-------------------------------------- 306

  Fly   636 HYPIEISADPPKDTASAAYIDNFLDKYLIDTATMEVTEETAPEAVQAQANGHAKISSDDDILVET 700
                          ..|||::
  Rat   307 --------------NEAAYLE-------------------------------------------- 313

  Fly   701 GRDLVAIDTLQGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDALIARSPSEEFAFDVP 765
                             :|:|.|        .|:
  Rat   314 -----------------INHIFN--------LEV------------------------------- 322

  Fly   766 KDPFLSPYWASDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQVDLEILEGLPHG----- 825
                 ||..|.|:.::|||||.:::...|...||.:::.|:|:..|..|....||...||
  Rat   323 -----SPLLADDKTIAQLPETLLVSNEYDVLRDDSILYKKRLEDQGVPVTWCHLEDGFHGCIMLF 382

  Fly   826 ---FLNFTMLSNEAMEGSKKCIKSLQ 848
               .|:|. .|::||..:...||.::
  Rat   383 DKKALSFP-CSHKAMSSTVSFIKGIK 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	26/102 (25%)
		Aes	350..>537	CDD:223730	50/206 (24%)
		Abhydrolase	395..>539	CDD:304388	39/163 (24%)
		Abhydrolase	<767..827	CDD:304388	20/67 (30%)
RGD1563334	XP_578509.2	Aes	<96..404	CDD:223730	91/517 (18%)
		Abhydrolase	114..380	CDD:304388	79/460 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263520at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820