Protein Alignment Hsl and RGD1559644

DIOPT Version :9

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: XP_038967499.1
• Gene: RGD1559644 / 366498
• RGDID: 1559644
• Length: 407
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 118/616 - (19%)
• Similarity: 179/616 - (29%)
• Gaps: 238/616 - (38%)

  Fly   254 LWTSGKYLMNPELRARRIVNISQNAKIDF--CKSFWFLAESEMMHKLPSIVGSSIKVNRLIELPA 316
            :|...|:.:..|:.:    ::....|:..  |...:.:|...::.||           |:..:|
  Rat    21 IWAVVKHFLTAEISS----SLQHPVKLRLMQCVVLFTIALGNILQKL-----------RICSMP- 69

  Fly   317 EPLKLPRRKNFKASDNLSSDVNQNQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGMLGEGRY 381
                        :......|:...:.|...|   |...|.|   .:.|||...:..|..|..|
  Rat    70 ------------SFIKFLHDLRGRKKDPTLV---VTNMHFG---TIPVRLFQPKAVSSNLRRG-- 114

  Fly   382 RGWHKPIPPSPSILFHCHGGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEV 446
                        |:|. ||||.:..|...:.......|...|..:|||.|...|:...|....:.
  Rat   115 ------------IIFF-HGGGALFGSLNLYHRLCSFLARETDSVLLSVGYRKLPDHHHPVIHLDC 166

  Fly   447 YYAYCWLLNNTELLGTTAERVVCAGDSAGANLSIGVALKCIEQGVRVPDGLFLAYCPTLVSFVPS 511
            ..|....|.|.:..|....|||.||:|.|     |.|:..:.|.:...|.|     |.:
  Rat   167 LNASIHFLKNLQTYGVDPSRVVMAGESVG-----GWAVATVTQALACQDKL-----PQI------ 215

  Fly   512 PARLLCLMDPLLPFGFMMRCLRAYAAPAQETLQQNAKQVEDAAQIRNVPKSNVGSLNSSRRTSMA 576
              |...|:.|:                    ||....|:....|.||||
  Rat   216 --RAQVLITPI--------------------LQGVNFQLPSQLQKRNVP---------------- 242

  Fly   577 RSPLSPLEASMNPDDESSDTFASASASYHSQTVERTDLPHTEGDNSSCVSFEDDSQPIVHYPIEI 641
                                            :...||..|
  Rat   243 --------------------------------LLTRDLMIT------------------------ 251

  Fly   642 SADPPKDTASAAYIDNFLDKYL-IDTATME--VTEETAPEAVQAQANGHAKISSDDDILVE-TGR 702
                            |..:|| ||.:...  :|....|..:..:   ::|..|.|:|... .|:
  Rat   252 ----------------FFCRYLNIDLSWKNAILTGACVPPDMWKK---YSKWLSSDNIPQRFKGK 297

  Fly   703 DLVAIDTLQGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDALIARSPSEEFAFDVPK- 766
            |.                          |.|..|                   |..|.|:...|
  Rat   298 DF--------------------------SPEFLG-------------------PFNETAYLETKH 317

  Fly   767 --DPFLSPYWASDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQVDLEILEGLPHGFLNF 829
              |..:||..|.|:.::|||:|.:|:...|...||.:::.|:|:..|..|....:|...||.:.|
  Rat   318 VLDEKISPLLADDKIIAQLPDTFLLSCEHDILRDDTLLYKKRLEDQGVPVTWHHVEDGFHGCIIF 382

  Fly   830 TMLSNEAMEGSKKCIKSLQTLLQTDSKTKNI 860
              ..|:..  |..|  |:..|..|.|..|.|
  Rat   383 --FDNQFF--SFPC--SMNALNPTISYIKGI 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	20/123 (16%)
		Aes	350..>537	CDD:223730	44/186 (24%)
		Abhydrolase	395..>539	CDD:304388	34/143 (24%)
		Abhydrolase	<767..827	CDD:304388	20/59 (34%)
RGD1559644	XP_038967499.1	Abhydrolase_3	115..380	CDD:400284	86/439 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263520at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820