Protein Alignment Hsl and Aadacl4fm5

DIOPT Version :10

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001119788.1
• Gene: Aadacl4fm5 / 329993
• MGIID: 2685284
• Length: 393
• Species: Mus musculus
• Alignment Length: 601
• Identity: 103/601 - (17%)
• Similarity: 173/601 - (28%)
• Gaps: 266/601 - (44%)

  Fly   254 LWTSGKYLMNPELRARRIVNISQNAKIDF--CKSFWFLAESEMMHKLPSIVGSSIKVNRLIELP- 315
            :|...::.:..|:.:    .:...||:.|  |...:.:....::.||           |:..:|
Mouse    21 VWAIIQHFLTVEIPS----TLKHPAKLRFLHCMLLYLITLGNILEKL-----------RICSIPR 70

  Fly   316 ----AEPLKLPRRKNFKASDNLSSDVNQNQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGML 376
                .:.|.|.|:             |.|        :.|...|.|   .|.|||...:..|...
Mouse    71 FLQFVQDLILIRK-------------NSN--------VAVTDMHFG---TVPVRLFKPKEASSKY 111

  Fly   377 GEGRYRGWHKPIPPSPSILFHCHGGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPR 441
            ....|.|.                |.|:|     ||         .|..:|.|.|...|:...|.
Mouse   112 RRDTYHGL----------------GSFLA-----HE---------TDSLVLLVGYRKLPDYHHPV 146

  Fly   442 ALQEVYYAYCWLLNNTELLGTTAERVVCAGDSAGANLSIGVALKCIEQGVRVPDGLFLAYCPTLV 506
            ..::...|..:.|.|.|:||....|||..|||.|     |.|:..:.|               ::
Mouse   147 PFKDCLNATIYFLKNLEILGVDPSRVVLCGDSLG-----GWAVATVTQ---------------VL 191

  Fly   507 SFVPSPARL--LCLMDPLLPF-GFMMRCLRAYAAPAQETLQQNAKQVEDAAQIRNVPKSNVGSLN 568
            :.:|:..|:  ..|:.|:|.| .|.:           .:.|||          :|||
Mouse   192 TSMPNLPRIQTQVLIYPILHFINFQL-----------PSYQQN----------KNVP-------- 227

  Fly   569 SSRRTSMARSPLSPLEASMNPDDESSDTFASASASYHSQTVERTDLPHTEGDNSSCVSFEDDSQP 633
                 .:.|                 |........|.:     .||..|:..::..|
Mouse   228 -----FLTR-----------------DMLLMCVCKYLA-----IDLSWTDAMSTGAV-------- 257

  Fly   634 IVHYPIEISADPPKDTASAAYIDNFLDKYLIDTATMEVTEETAPEAVQAQANGHAKISSDDDILV 698
                   |..|..|........||...::.        .::|.||.:
Mouse   258 -------IPLDKWKKYRKWLSYDNIPRRFW--------RQDTQPEVL------------------ 289

  Fly   699 ETGRDLVAIDTLQGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDALIARSPSEEFAFD 763
                         |...||.                    .:..:.|.|.:
Mouse   290 -------------GPFNEAA--------------------YLETKHVWNAE-------------- 307

  Fly   764 VPKDPFLSPYWASDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQVDLEILEGLPHGFLN 828
                  :||..|.|:.::|||:|.:::...|...||.:::.::|:.          :|:|..:.:
Mouse   308 ------ISPLLADDKIIAQLPKTFLVSCEHDVLRDDALLYKRRLED----------QGIPVSWYH 356

  Fly   829 FTMLSNEAMEGSKKCI 844
                   |.:|...||
Mouse   357 -------AEDGFHACI 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:461882	23/128 (18%)
		alpha/beta hydrolases	395..>539	CDD:473884	34/146 (23%)
		Aes	<767..838	CDD:440422	15/70 (21%)
Aadacl4fm5	NP_001119788.1	alpha/beta hydrolases	114..365	CDD:473884	78/467 (17%)