Protein Alignment Hsl and Aadacl4fm1

DIOPT Version :10

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001127994.1
• Gene: Aadacl4fm1 / 298623
• RGDID: 1308878
• Length: 412
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 105/555 - (18%)
• Similarity: 158/555 - (28%)
• Gaps: 232/555 - (41%)

  Fly   317 EPLKLPRRKNFK--ASDNLSSDVNQNQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGMLGEG 379
            |.:|:.....|.  ..|:|:...|.    |.||:    ..|.|   .:.||:...:..|.
  Rat    66 EKMKICSMSQFVCFVQDSLAPKENL----GMFVK----DLHFG---TIPVRIFHPKAASS----- 114

  Fly   380 RYRGWHKPIPPSPSILFHCHGGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQ 444
                     .|...|:| |||||.:..|..|:.......|...|..::||.|...|....|....
  Rat   115 ---------KPRRGIIF-CHGGGALIGSLDSYHNLCAFLARETDSVLMSVGYRKLPYYHHPSLYY 169

  Fly   445 EVYYAYCWLLNNTELLGTTAERVVCAGDSAGANLSIGVALKCIEQGVRVPD--GLFLAYCPTLVS 507
            :...|....||:.::.|....|||..|||.|..:: .:..:.:.....:|.  ...|.| |.|.:
  Rat   170 DCLNASIHFLNSLKVYGVDPSRVVICGDSIGGAVA-AIVTQTLSSRTDIPKIRAQVLIY-PVLQA 232

  Fly   508 F-VPSPARLLCLMDPLLPFGFMMRCLRAYAA---PAQETLQQNA-------KQVEDAAQIRNVPK 561
            | ..||:.|..:..|.|...|.:.|:..|.|   ..::|:...|       |:.|......|:||
  Rat   233 FYFQSPSHLTNINIPFLTQEFFITCVCKYLAIDLSWKDTMLTGASISPSAWKKYEKWLSPENIPK 297

  Fly   562 SNVGSLNSSRRTSMARSPLSPLEASMNPDDESSDTFASASASYHSQTVERTDLPHTEGDNSSCVS 626
                     |..:..|.|.||                                          ..
  Rat   298 ---------RFKTEYRPPESP------------------------------------------TP 311

  Fly   627 FEDDSQPIVHYPIEISADPPKDTASAAYIDNFLDKYLIDTATMEVTEETAPEAVQAQANGHAKIS 691
            |.|                      |||::                            ..||
  Rat   312 FND----------------------AAYLE----------------------------TKHA--- 323

  Fly   692 SDDDILVETGRDLVAIDTLQGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDALIARSP 756
                                                                  .|:|
  Rat   324 ------------------------------------------------------MNVD------- 327

  Fly   757 SEEFAFDVPKDPFLSPYWASDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQVDL-EILE 820
                         :||..|.|:.::||||..|::|:.|...||.:::.|:|:..|..|.. .:::
  Rat   328 -------------ISPLLADDKIITQLPEAFIVSLHWDIVRDDVLLYKKRLEDHGVPVTWHHVVD 379

  Fly   821 GLPHG--------FLNFTMLSNEAMEGSKKCIKSL 847
            |. ||        |.:|....| .|......||.|
  Rat   380 GF-HGCMLLFDKKFFSFPCSVN-IMHAVVSYIKGL 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:461882	14/60 (23%)
		alpha/beta hydrolases	395..>539	CDD:473884	41/149 (28%)
		Aes	<767..838	CDD:440422	23/79 (29%)
Aadacl4fm1	NP_001127994.1	alpha/beta hydrolases	120..385	CDD:473884	83/446 (19%)