Protein Alignment Hsl and RGD1308878

DIOPT Version :9

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001127994.1
• Gene: RGD1308878 / 298623
• RGDID: 1308878
• Length: 412
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 105/555 - (18%)
• Similarity: 158/555 - (28%)
• Gaps: 232/555 - (41%)

  Fly   317 EPLKLPRRKNFK--ASDNLSSDVNQNQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGMLGEG 379
            |.:|:.....|.  ..|:|:...|.    |.||:    ..|.|   .:.||:...:..|.
  Rat    66 EKMKICSMSQFVCFVQDSLAPKENL----GMFVK----DLHFG---TIPVRIFHPKAASS----- 114

  Fly   380 RYRGWHKPIPPSPSILFHCHGGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQ 444
                     .|...|:| |||||.:..|..|:.......|...|..::||.|...|....|....
  Rat   115 ---------KPRRGIIF-CHGGGALIGSLDSYHNLCAFLARETDSVLMSVGYRKLPYYHHPSLYY 169

  Fly   445 EVYYAYCWLLNNTELLGTTAERVVCAGDSAGANLSIGVALKCIEQGVRVPD--GLFLAYCPTLVS 507
            :...|....||:.::.|....|||..|||.|..:: .:..:.:.....:|.  ...|.| |.|.:
  Rat   170 DCLNASIHFLNSLKVYGVDPSRVVICGDSIGGAVA-AIVTQTLSSRTDIPKIRAQVLIY-PVLQA 232

  Fly   508 F-VPSPARLLCLMDPLLPFGFMMRCLRAYAA---PAQETLQQNA-------KQVEDAAQIRNVPK 561
            | ..||:.|..:..|.|...|.:.|:..|.|   ..::|:...|       |:.|......|:||
  Rat   233 FYFQSPSHLTNINIPFLTQEFFITCVCKYLAIDLSWKDTMLTGASISPSAWKKYEKWLSPENIPK 297

  Fly   562 SNVGSLNSSRRTSMARSPLSPLEASMNPDDESSDTFASASASYHSQTVERTDLPHTEGDNSSCVS 626
                     |..:..|.|.||                                          ..
  Rat   298 ---------RFKTEYRPPESP------------------------------------------TP 311

  Fly   627 FEDDSQPIVHYPIEISADPPKDTASAAYIDNFLDKYLIDTATMEVTEETAPEAVQAQANGHAKIS 691
            |.|                      |||::                            ..||
  Rat   312 FND----------------------AAYLE----------------------------TKHA--- 323

  Fly   692 SDDDILVETGRDLVAIDTLQGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDALIARSP 756
                                                                  .|:|
  Rat   324 ------------------------------------------------------MNVD------- 327

  Fly   757 SEEFAFDVPKDPFLSPYWASDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQVDL-EILE 820
                         :||..|.|:.::||||..|::|:.|...||.:::.|:|:..|..|.. .:::
  Rat   328 -------------ISPLLADDKIITQLPEAFIVSLHWDIVRDDVLLYKKRLEDHGVPVTWHHVVD 379

  Fly   821 GLPHG--------FLNFTMLSNEAMEGSKKCIKSL 847
            |. ||        |.:|....| .|......||.|
  Rat   380 GF-HGCMLLFDKKFFSFPCSVN-IMHAVVSYIKGL 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	14/60 (23%)
		Aes	350..>537	CDD:223730	47/189 (25%)
		Abhydrolase	395..>539	CDD:304388	41/149 (28%)
		Abhydrolase	<767..827	CDD:304388	20/68 (29%)
RGD1308878	NP_001127994.1	Aes	<102..387	CDD:223730	87/480 (18%)
		Abhydrolase	120..386	CDD:304388	83/447 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263520at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820