Protein Alignment Hsl and RGD1560324

DIOPT Version :9

• Sequence 1: NP_611463.1
• Gene: Hsl / 37289
• FlyBaseID: FBgn0034491
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001099906.1
• Gene: RGD1560324 / 295072
• RGDID: 1560324
• Length: 401
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 104/574 - (18%)
• Similarity: 179/574 - (31%)
• Gaps: 231/574 - (40%)

  Fly   283 CKSFWFLAESEMMH-KLPS---------IVGSSIKVNRLIELPAEPLKLPRRKNF---------- 327
            |..|:|:..:..:: .:|.         |:.:.:|::.|.....|.:.|.:.:.|
  Rat     7 CFGFFFIFLAYYIYIPIPENVEEPWKVRIIDAGMKISSLTATWLENMGLMKFEEFFGILMGIQDT 71

  Fly   328 KASDNLSSDVNQNQGDGDFVEIPVPTAHLGPGLPVSVRLLSARRRSGMLGEGRYRGWHKPIPPSP 392
            ||    .||.|....|.||.:||             |||...:|.|     .|.|         |
  Rat    72 KA----VSDENITVIDTDFNDIP-------------VRLYLPKRES-----ERKR---------P 105

  Fly   393 SILFHCHGGGFVAQSSK--SHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLLN 455
            :::: .|||.|:..|.|  .::...|..|..||..:::.||.|||:..||.||::......:.|.
  Rat   106 AVIY-IHGGAFILGSFKMLPYDSMNRWTANKLDAVVIAPDYRLAPQYLFPAALEDCVLVTKFFLQ 169

  Fly   456 NTELLGTTAE--RVVCAGDSAGANLSIGVALKCIEQGVRVPDGLFLAYCPTLVSFVPSPARLLCL 518
            :..|.....:  |:..:|||:|..|
  Rat   170 DKVLAKYRVDPTRICISGDSSGGTL---------------------------------------- 194

  Fly   519 MDPLLPFGFMMRCLRAYAAPAQETLQQNAKQVEDAAQIRNVPKSNVGSLNSSRRTSMARSPLSPL 583
                             ||...:.||       |..:.:|..::
  Rat   195 -----------------AATVTQLLQ-------DDPEYKNKIRA--------------------- 214

  Fly   584 EASMNPDDESSDTFASASASY-HSQTVERTDLPHTEGDNSSCVSFEDDSQPIVHYPIEI--SADP 645
            :..:.|..::.||...:...| |...:.|     ......:|:...:|.:    .|..|  :|..
  Rat   215 QTLLYPGLQALDTLMPSFREYEHGPFLTR-----KVAIKMTCLYLSEDKE----LPKTILRNAHV 270

  Fly   646 PKDTASAAYIDNFLDKYLIDTATMEVTEETAPEAVQAQANGHAKISSDDDILVETGRDLVAIDTL 710
            ||::.......|:.| :|             ||..:                    ::.|..:.:
  Rat   271 PKESRHLFKFVNWSD-FL-------------PEKYK--------------------KNHVYTEPV 301

  Fly   711 QGRLQEAVNNITNTLTRCTQSYEIHGSNVMAQQDVRNMDALIARSPSEEFAFDVPKDPFLSPYWA 775
            .|:|..:                 |...|                           |..:||...
  Rat   302 LGKLSAS-----------------HPGLV---------------------------DSRVSPLLV 322

  Fly   776 SDEWLSQLPETKILTLNMDPCLDDCVMFAKKLKRLGRQVDLEILEGLPHGFLNF 829
            :|..|.:||.|.|||...|...||.:::..:|:.:|.....:.:|...||.::|
  Rat   323 NDSQLQKLPLTYILTCEHDILRDDGLIYVTRLRNVGVTFTHDHIEDGIHGAVSF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	25/112 (22%)
		Aes	350..>537	CDD:223730	36/190 (19%)
		Abhydrolase	395..>539	CDD:304388	29/147 (20%)
		Abhydrolase	<767..827	CDD:304388	19/59 (32%)
RGD1560324	NP_001099906.1	Aes	71..389	CDD:223730	94/510 (18%)
		Abhydrolase_3	107..372	CDD:285143	73/437 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263520at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820