DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsl and SPAC1039.03

DIOPT Version :9

Sequence 1:	NP_611463.1	Gene:	Hsl / 37289	FlyBaseID:	FBgn0034491	Length:	881	Species:	Drosophila melanogaster
Sequence 2:	NP_594994.1	Gene:	SPAC1039.03 / 2543023	PomBaseID:	SPAC1039.03	Length:	341	Species:	Schizosaccharomyces pombe

Alignment Length:	215	Identity:	54/215 - (25%)
Similarity:	83/215 - (38%)	Gaps:	24/215 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 DNLSSDVNQNQGDGDFV------EIPVPTAHLGPGLPVSVRLLSARRRSGMLGEGRYRGWHKPIP 389
            |.|.::.|...|..:.:      :|.:|..|......|..|:.   |..|...||   ||
pombe    47 DFLRNNGNVMPGQSELLPVESTEDITIPRKHTKAPSGVPSRIF---RPHGTAPEG---GW----- 100

  Fly   390 PSPSILFHCHGGGFVAQSSKSHELYLRDWAVALDCPILSVDYSLAPEAPFPRALQEVYYAYCWLL 454
              |..|:. ||||:|..:..:...:.........|.:::|||.||||.|||..:.:.:.|..:..
pombe   101 --PCFLWF-HGGGWVLGNINTENSFATHMCEQAKCVVVNVDYRLAPEDPFPACIDDGWEALLYCY 162

  Fly   455 NNTELLGTTAERVVCAGDSAGANLSIGVALKCIEQGVRVP----DGLFLAYCPTLVSFVPSPARL 515
            .|.:.||....::...|.|||.|::..::.|........|    ..|.:..|....:.....:..
pombe   163 ENADTLGINPNKIAVGGSSAGGNIAAVLSHKVAASPANFPPLVLQLLVVPVCDNTANAKTHKSWE 227

  Fly   516 LCLMDPLLPFGFMMRCLRAY 535
            |....|.||...||...|.|
pombe   228 LFENTPQLPAAKMMWYRRHY 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsl	NP_611463.1	HSL_N	51..376	CDD:283906	11/50 (22%)
		Aes	350..>537	CDD:223730	49/190 (26%)
		Abhydrolase	395..>539	CDD:304388	38/145 (26%)
		Abhydrolase	<767..827	CDD:304388
SPAC1039.03	NP_594994.1	Aes	55..341	CDD:223730	51/207 (25%)
SPAC1039.03	NP_594994.1	Abhydrolase_3	103..313	CDD:285143	38/146 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto102063
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900