DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ate1 and ATE1

DIOPT Version :9

Sequence 1:	NP_001261101.1	Gene:	Ate1 / 37288	FlyBaseID:	FBgn0025720	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_196189.1	Gene:	ATE1 / 830454	AraportID:	AT5G05700	Length:	632	Species:	Arabidopsis thaliana

Alignment Length:	640	Identity:	205/640 - (32%)
Similarity:	283/640 - (44%)	Gaps:	189/640 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SIVSYYGSQQSKCGYC-AGANCSLSHGMHAYQLDCRDYQDLIDRGWRRCGYYCYKLRNQETCCPC 67
            |::..:|.::|.|||| :.|..|:|||:.|..|...|||.||||||||.|.|.||....:||||.
plant    19 SVIDDHGRRKSTCGYCKSPARSSISHGLSAQTLTVYDYQALIDRGWRRSGTYLYKHEMDKTCCPP 83

  Fly    68 YTIKCNGLEFKLSKSNKRILRRINRFLRDGK-----RESKPEAGDGD-------------GEADA 114
            |||:....:|..:|..:|:.||:.||| |||     ||.:..:..||             .|.:.
plant    84 YTIRLKASDFVPTKEQQRVSRRLERFL-DGKLDVQPREQRGASSSGDVSDTRRKTLGAAKSEENK 147

  Fly   115 DYAIVAPEVTASEPQP--------------QLPDKSPPVINVEQVASLATAQRKPTKQAT----- 160
            ....|..:::.:..|.              |:|..|        |..:..|:||...:.|
plant   148 KVEAVMDDLSKNIDQAVQLCIRSGEFPSNMQIPKAS--------VKKVFCARRKKLAEGTEQILY 204

  Fly   161 --------AAAV------EAPTLGSNKSSLLSSSAAA--------------PISNKPCK------ 191
                    |||:      |...:.|.:.:.||....:              .:|.|.||
plant   205 TSNIAFPIAAAIKRIQTSEKEGINSAEGNRLSPETISEMLLSAMHKVGETPDVSIKVCKGHINFL 269

  Fly   192 -KAKQMRLDRRLAKLGDSASYSTKSLTQEKTLRDFLNTDSETN---KHRLKIVLVASS-DTERTC 251
             .||....||.:...| :.|....||...:||.  ...|||.:   |.:|:|.|..|| |.|..
plant   270 SSAKDSFSDRDVVPNG-NISRGANSLDGSETLH--AKKDSENHQARKRKLEIHLKRSSFDPEEH- 330

  Fly   252 ADAVIALYRKYQITVHNDNPARLTLASMQRFLVKSPLKNEKPWDG----PEMGYGSFHQQYWLDD 312
                 .||::||:.||||.|..:..:|.:||||.|||.:.:| .|    |..|:|||||||.:|.
plant   331 -----ELYKRYQLKVHNDKPGHVVESSYRRFLVDSPLIDVQP-SGDEKVPPCGFGSFHQQYRIDG 389

  Fly   313 KLIAVGVIDILPGCVSSVYFFYDPDYSFLSLGTYGSLREIELVQSLAEKVPSLKYYYMGFYIHSC 377
            :||||||:||||.|:||||.|:||||:|||||.|.:::||..|.....:.|||:|||:|:|||||
plant   390 RLIAVGVVDILPKCLSSVYLFWDPDYAFLSLGKYSAIQEINWVIENQARCPSLQYYYLGYYIHSC 454

  Fly   378 PKMRYKGKLSPSYLLCPETYEWLPLTDVIRAKLDEHKYQRLNE-------------------DPA 423
            .|||||....||.||||..::|:|. :|.|..||:..|..|::                   :||
plant   455 SKMRYKAAYRPSELLCPLRFQWVPF-EVARPMLDKKPYVILSDIAISHNQCSLLAGASETLVEPA 518

  Fly   424 A---------------------------------------------------------RDVNEFL 431
            |                                                         .|:|..|
plant   519 ASEHEDMEQGETNDNFMGCSDEDEDEDEDDDDDDDDDEEMYETESEDSHIESDPGSKDNDINNIL 583

  Fly   432 MEHLDEVKLLLGGRTRTDYKHFRQL---RGTVSDDDIIIEYSKLVGKECARRMLY 483
            :.       |.|.:.|  ||..||:   .|....:.::..|.|:||.|.:.||:|
plant   584 IG-------LYGSQYR--YKEMRQIITPVGRKQLEPMLQSYRKVVGAELSERMVY 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ate1	NP_001261101.1	ATE_N	14..85	CDD:282259	36/71 (51%)
Ate1	NP_001261101.1	ATE_C	256..395	CDD:282260	80/142 (56%)
ATE1	NP_196189.1	ATE_N	29..101	CDD:398189	36/71 (51%)
ATE1	NP_196189.1	ATE_C	328..470	CDD:398190	79/148 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	156	1.000	Domainoid score	I1318
eggNOG	1	0.900	-	-		E1_COG2935
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1000
OMA	1	1.010	-	-		QHG55132
OrthoDB	1	1.010	-	-		D1446907at2759
OrthoFinder	1	1.000	-	-		FOG0004464
OrthoInspector	1	1.000	-	-		otm2707
orthoMCL	1	0.900	-	-		OOG6_103364
Panther	1	1.100	-	-	LDO	PTHR21367
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840