DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ate1 and ATE2

DIOPT Version :9

Sequence 1:	NP_001261101.1	Gene:	Ate1 / 37288	FlyBaseID:	FBgn0025720	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_187733.1	Gene:	ATE2 / 820295	AraportID:	AT3G11240	Length:	605	Species:	Arabidopsis thaliana

Alignment Length:	605	Identity:	184/605 - (30%)
Similarity:	273/605 - (45%)	Gaps:	150/605 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SIVSYYGSQQSKCGYC-AGANCSLSHGMHAYQLDCRDYQDLIDRGWRRCGYYCYKLRNQETCCPC 67
            |||:..|..:|.|||| :....|:|||:...:|...|||.|:|.||||.|.|.||...::||||.
plant    23 SIVADCGRNKSTCGYCKSSTRFSISHGLWTERLTVNDYQALLDSGWRRSGCYLYKPEMEKTCCPS 87

  Fly    68 YTIKCNGLEFKLSKSNKRILRRINRFLRDGKRESKP--EAGDGDGEADADYAI-------VAPEV 123
            |||:....:|..||..:|:.|||.||| ||:.::||  :..|.|.....:.::       .|...
plant    88 YTIRLKASDFVPSKEQQRVRRRIERFL-DGELDAKPSEQTEDQDVSFSREVSVSVKKSLGAAKRE 151

  Fly   124 TASEPQPQLPDKSPPVINVEQ------------------VASLATAQRKPTKQATAAAVEAPTLG 170
            ..:|.:|.:.|.|..:.|..|                  |..:.:|:||...:
plant   152 KNNELEPIMKDLSEQIDNAVQKCIQSGEFPSNVQIPKASVKKVFSAKRKKLAE------------ 204

  Fly   171 SNKSSLLSSSAAAPI-----------------SNKPCKKAKQMRLDRRLAKLGDSASYSTKSLTQ 218
            .::..|.:|:.|.||                 .|:...:|...:|...:.|:|:...:|.|   .
plant   205 GSEDLLYTSNIAFPIVAAMKHTQTLEKGKNVEENRLSPEAVSEKLLSAMNKVGEFTGFSVK---V 266

  Fly   219 EKTLRDFLNTDSETNKHRLKIVLVASSDTERTCADAV---------------------------I 256
            .|...:||:....|:..|       :...|..||..:                           .
plant   267 SKGHINFLSATQVTSSDR-------NEGEESLCATTIKSSSNKLHARKRKLEMHLKRSSFEPEEY 324

  Fly   257 ALYRKYQITVHNDNPARLTLASMQRFLVKSPLKNEKPWDG-------PEMGYGSFHQQYWLDDKL 314
            .||::||:.||||.|..::..|.:||||.:|| .|.|..|       |..|:|||||||.:||:|
plant   325 ELYKRYQMKVHNDKPESISETSYKRFLVDTPL-TEVPSSGYDDEEKIPLCGFGSFHQQYRVDDRL 388

  Fly   315 IAVGVIDILPGCVSSVYFFYDPDYSFLSLGTYGSLREIELVQSLAEKVPSLKYYYMGFYIHSCPK 379
            ||||||||||.|:||.|.|:|||::.||||.|.:|:||:.|:.......:|:|||:|:|||||.|
plant   389 IAVGVIDILPKCLSSKYLFWDPDFASLSLGNYSALQEIDWVKQNQAHCSTLEYYYLGYYIHSCNK 453

  Fly   380 MRYKGKLSPSYLLCPETYEWLPLTDVIRAKLDEHKY------QRLNEDPAARDVNEFLMEHLDEV 438
            ||||....||.||||..|:|:|. :|.:..||:..|      .:::...::...:|.|:|...|.
plant   454 MRYKAAYRPSELLCPLRYQWVPF-EVAKPLLDKKPYSVLSNISKVSSSSSSPQASETLLESTSEH 517

  Fly   439 KLLLGGRTRTD-------------------------------------YKHFRQLRGTVSD---D 463
            :.:..|.|..|                                     ||...:.:..|..   :
plant   518 EDMEQGDTNDDDDEMYNSDEDSDSDSSSSRNRSDITNILISLNGPRLRYKDIPRFKNPVVQKQLE 582

  Fly   464 DIIIEYSKLVGKECARRMLY 483
            .:::.|.|:||.|.:..|:|
plant   583 SMLVSYRKVVGAELSEIMVY 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ate1	NP_001261101.1	ATE_N	14..85	CDD:282259	33/71 (46%)
Ate1	NP_001261101.1	ATE_C	256..395	CDD:282260	78/145 (54%)
ATE2	NP_187733.1	ATE_N	32..105	CDD:282259	33/72 (46%)
		Arg_tRNA_synt_N	161..273	CDD:214975	21/126 (17%)
		ATE_C	322..468	CDD:282260	77/146 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	156	1.000	Domainoid score	I1318
eggNOG	1	0.900	-	-		E1_COG2935
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1000
OMA	1	1.010	-	-		QHG55132
OrthoDB	1	1.010	-	-		D1446907at2759
OrthoFinder	1	1.000	-	-		FOG0004464
OrthoInspector	1	1.000	-	-		otm2707
orthoMCL	1	0.900	-	-		OOG6_103364
Panther	1	1.100	-	-	O	PTHR21367
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840