DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and SOA1

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_012100.1	Gene:	SOA1 / 854640	SGDID:	S000001428	Length:	542	Species:	Saccharomyces cerevisiae

Alignment Length:	562	Identity:	116/562 - (20%)
Similarity:	198/562 - (35%)	Gaps:	172/562 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RVNLSINIIAMVEDTSS---------HE--------NGTEVEALPDYGPRYNWTQSDQALL---- 73
            :..||::..::..|:.|         |:        ..:..|.|..:.|.:.||:.::..|
Yeast    13 KAQLSVSAESLTSDSESISHNPFDDFHKAERWRKVYESSGYEGLSKFDPEFTWTKDEEKKLVRKM 77

  Fly    74 ------------------------------------------LG--AYFYGYMITSLPAGTLAEM 94
                                                      ||  .|...::.:.||...|::.
Yeast    78 DLKIFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVYLVIFLASELPGNLLSKR 142

  Fly    95 LGARNVAGYSCLVAGILTALTPAAAAWDKYAVFAVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGK 159
            .|...|.....::..:: .:|.|... ::....|.|.|:|.:.|...|.....:|.:....|.
Yeast   143 FGPERVIPVQIVLWSVI-CITQAGLK-NRGQFIATRCLLGMVQGGFIPDNILYLSYYYTGAEL-- 203

  Fly   160 FVASLMGGTFGTVITW---PI---------SGVI----IENL-GWDWAFYIVGIFVLVVVAIWFY 207
                    ||.....|   |:         ||:|    |.|| ||.:.|.|.|...|.|....||
Yeast   204 --------TFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFIIEGFLSLSVGVASFY 260

  Fly   208 LVADTPAQ------HSTISLKEREYIES-----------SLGDTLSNKKKWPPYKELVLSLPFWS 255
            |:...|.|      |...|| ..||.|.           |.|| :||::. ..:||::.:|..:.
Yeast   261 LMRRGPTQTGESAFHKGKSL-FTEYEEKIMVNRILRDDPSKGD-MSNRQP-VTFKEILYTLTEFD 322

  Fly   256 LMMLHYGSMWGLFFL-ITA------TPKFLSEVLGFNLSSAGFLS---SLPHVARLLCAFGFGAV 310
            |        |.||.. |||      ...:||.:|. :|:.:.|||   ::|..|.||......|:
Yeast   323 L--------WPLFIQGITAFISLQTVGSYLSLILK-SLNYSTFLSNILAIPGQALLLINLPLAAL 378

  Fly   311 ADWIRRRGWLSVTRMRKAFCL---PSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNG-----A 367
                     ||.....|:.|:   ...:||.::.::......:|::...::|..||...     |
Yeast   379 ---------LSRKLKEKSLCVGIANVWVLPFIVSLVALPTDTNPWIKYILLTGILGLPYTHSILA 434

  Fly   368 ATASNLANSQDLAPNYAGT-LYGIINCVGTTPGIFSPLIVAAFTKNENTIDQWHWV----FIIGA 427
            ...|.::||  :.....|| ||.:...||.       :|.:...:|:   |:.::.    .::|.
Yeast   435 GWVSEISNS--VRSRTVGTALYNMSAQVGA-------IIASNMYRND---DKPYYTRGNKILLGF 487

  Fly   428 AAY----ILPALFFWVF-GSGKIQKWNEVQTTESREDIVNTK 464
            ..:    .:...|:::. ...|.:|||.:...|....:..||
Yeast   488 TCFNICMAVATKFYYISRNKYKDRKWNSMTKEEQINYLDTTK 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	113/550 (21%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	103/493 (21%)
SOA1	NP_012100.1	MFS_FEN2_like	76..496	CDD:340885	97/464 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I1824
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050