DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and slc17a7

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	460	Identity:	146/460 - (31%)
Similarity:	256/460 - (55%)	Gaps:	15/460 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CFYVPKRINLAIMLFMACLLSYMMRVNLSINIIAMVEDTSSHE-NGTEVEALPDYGPRYNWTQSD 69
            ||.:|:|..:|||..:...:|:.:|.||.:.|::||.:.:.:: |...:|.     .::.|....
Frog    56 CFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNNTVYKGNKIVIEQ-----AQFTWDPET 115

  Fly    70 QALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKYAVFAVRFLIG 134
            ..::.|::|:||::|.:|.|.:.:...|..|.|::.:....|..|.|:||......|..||.|.|
Frog   116 VGMIHGSFFWGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACVICVRILQG 180

  Fly   135 FLNGVVYPCCHSLVSKWSPPDEKGKFVASLMGGTF-GTVITWPISGVIIENLGWDWAFYIVGIFV 198
            .:.||.||.||.:.|||:||.|:.:...:...|:: |.|:..|::||:::..||...||:.|.|.
Frog   181 LVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFG 245

  Fly   199 LVVVAIWFYLVADTPAQHSTISLKEREYIESSLGDT--LSN--KKKWPPYKELVLSLPFWSLMML 259
            ::....|..:..::||.|.|||.:|::|||.|:|::  |.|  .|...|:::...|:|.:::::.
Frog   246 IMWYMFWILVSYESPAIHPTISEEEKKYIEESIGESTGLMNPMAKFKAPWRKFFTSMPVYAIIVA 310

  Fly   260 HYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPH-VARLLCAFGFGAVADWIRRRGWLSVT 323
            ::...|..:.|:.:.|.:..||.||.:|..|.||:||| |..::...| |.:||::|.:..:|.|
Frog   311 NFCRSWTFYLLLISQPAYFEEVFGFEISKVGLLSALPHLVMTIIVPIG-GQIADFLRTKRIMSTT 374

  Fly   324 RMRKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGTLY 388
            .:||........:...:|:::.| .....|.::.:.:::||:|.|.:....|..|:||.||..|.
Frog   375 NVRKMMNCGGFGMEATLLLVVGY-SHSRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILM 438

  Fly   389 GIINCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWNEVQT 453
            ||.|.|||..|:..||||.|.||:: |.::|.:||:|.:..:....||:.:|.||:.|.|.|.:.
Frog   439 GISNGVGTLSGMVCPLIVGAMTKHK-TREEWQYVFLIASLVHYGGVLFYGIFASGEKQPWAEPEE 502

  Fly   454 TESRE 458
            |...:
Frog   503 TSDEK 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	145/454 (32%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	123/390 (32%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	142/448 (32%)
		MFS	67..490	CDD:119392	134/430 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920