DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and SLC17A1

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_016866688.1	Gene:	SLC17A1 / 6568	HGNCID:	10929	Length:	517	Species:	Homo sapiens

Alignment Length:	476	Identity:	137/476 - (28%)
Similarity:	220/476 - (46%)	Gaps:	35/476 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PCFYV-----PKRI--------NLAIMLFMACLLSYMMRVNLSINIIAMVEDTSSHE-NGTEVEA 55
            ||..:     ||::        .|:.::....::....|..|::.::.||..|..|. ..|..:.
Human    49 PCMQMDNRLPPKKVPGFCSFRYGLSFLVHCCNVIITAQRACLNLTMVVMVNSTDPHGLPNTSTKK 113

  Fly    56 LPD--YGPRYNWTQSDQALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAA 118
            |.|  ..|.|||:...|.::|.:..||.:|..:|.|..:.:...:.:.|::..::.:|:.|.|.|
Human   114 LLDNIKNPMYNWSPDIQGIILSSTSYGVIIIQVPVGYFSGIYSTKKMIGFALCLSSVLSLLIPPA 178

  Fly   119 A----AWDKYAVFAVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGKFVA-SLMGGTFGTVITWPIS 178
            |    ||    |...|.:.|...|:|......:..||:||.|:|:..: |..|...|..|...::
Human   179 AGIGVAW----VVVCRAVQGAAQGIVATAQFEIYVKWAPPLERGRLTSMSTSGFLLGPFIVLLVT 239

  Fly   179 GVIIENLGWDWAFYIVGIFVLVVVAIWFYLVADTPAQHSTISLKEREYIESSLGDTLSNKKKWPP 243
            |||.|:|||...|||.|.....|..:||.|..|.|..|..||:.|:|||.|||...:|:.::..|
Human   240 GVICESLGWPMVFYIFGACGCAVCLLWFVLFYDDPKDHPCISISEKEYITSSLVQQVSSSRQSLP 304

  Fly   244 YKELVLSLPFWSLMMLHYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFG 308
            .|.::.|||.|::....:...|....:...||.|::.:|..|:...|||||||::...:|....|
Human   305 IKAILKSLPVWAISTGSFTFFWSHNIMTLYTPMFINSMLHVNIKENGFLSSLPYLFAWICGNLAG 369

  Fly   309 AVADWIRRRGWLSVTRMRKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAATASNL 373
            .::|:...|..|||..:||.|.....:||.:..:.|.|.. ..:..:.|..|..|..|:.....:
Human   370 QLSDFFLTRNILSVIAVRKLFTAAGFLLPAIFGVCLPYLS-STFYSIVIFLILAGATGSFCLGGV 433

  Fly   374 -ANSQDLAPNYAGTLYGIINCVGTTPGIFSPLIVAAFT---KNENTIDQWHWVFIIGAAAYILPA 434
             .|..|:||.|    :|.|....|..|:...||.:..|   ..::....|...||:.||..:...
Human   434 FINGLDIAPRY----FGFIKACSTLTGMIGGLIASTLTGLILKQDPESAWFKTFILMAAINVTGL 494

  Fly   435 LFFWVFGSGKIQKW-NEVQTT 454
            :|:.:..:.:||.| .|.|.|
Human   495 IFYLIVATAEIQDWAKEKQHT 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	136/474 (29%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	119/395 (30%)
SLC17A1	XP_016866688.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810