DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and MFS14

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster

Alignment Length:	462	Identity:	152/462 - (32%)
Similarity:	251/462 - (54%)	Gaps:	25/462 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IMLFMACLLSYMMRVNLSINIIAMVED-TSSHENGTEVEALPD-----------YGPRYNWTQSD 69
            |:.|....:||..|||||:.::||.:: ||..:|.|.....|.           |   ||:||.:
  Fly    28 ILCFFCLAMSYAWRVNLSVALVAMTDNSTSLAQNNTNTGVAPSEPGFDFFNSERY---YNFTQKE 89

  Fly    70 QALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKYAVFAVRFLIG 134
            :..|..::|:||::|.:|.|.:|:..||:.:..|...:|.::|.|:|.:..:...|:..:||::|
  Fly    90 KGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPMSLQFGWVALAVMRFVMG 154

  Fly   135 FLNGVVYPCCHSLVSKWSPPDEKGKF-VASLMGGTFGTVITWPISGVIIEN-LGWDWAFYIVGIF 197
            ...|.|:|..|:|::||||.||:|.. .....|..||||:....||.|.:: |||...||:.|..
  Fly   155 LAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFGTVVMLATSGFIADSVLGWPSIFYLGGAC 219

  Fly   198 VLVVVAIWFYLVADTPAQHSTISLKEREYIESSLGD--TLSNKKKWP-PYKELVLSLPFWSLMML 259
            ..:.:..|:...|.||.:|..||..|.:||..|..|  ..|.:|..| |:|.:..||||.||:::
  Fly   220 GFIWMVFWYLFSASTPEEHRLISPGELKYITDSRSDGKMQSAEKLAPTPWKAIFSSLPFLSLLVV 284

  Fly   260 HYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFGAVADWIRRRGWLSVTR 324
            |...::|.:.|:...|.::.::...::.....|||||::..||.:|.|..::..::::..:|::.
  Fly   285 HCTHIFGYWLLLMQIPTYMKKIYHVDIKKGALLSSLPYMVMLLLSFFFVWLSKVLQKKEGMSLSF 349

  Fly   325 MRKAFCLPSHILPGVMLIILAYFGRD--PYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGTL 387
            .||.|....|.:|.:.||.|.|...|  | :.|.::|:::|.:||.......|..||:|||||||
  Fly   350 NRKIFNSIGHWIPMLSLIALGYVPADNAP-LAVTLLTLTVGISGATYLGFQVNHIDLSPNYAGTL 413

  Fly   388 YGIINCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWNEVQ 452
            .||.||........:|:||.....:|.::.:|..||::.||.|.|..|.|.:||..::|.|:..:
  Fly   414 MGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLGNLLFVIFGRTEVQWWDSPR 478

  Fly   453 TTESRED 459
              :::||
  Fly   479 --DNKED 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	150/455 (33%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	131/402 (33%)
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	150/452 (33%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	130/388 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970