DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and CG7091

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_650243.2	Gene:	CG7091 / 41590	FlyBaseID:	FBgn0038099	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	491	Identity:	121/491 - (24%)
Similarity:	210/491 - (42%)	Gaps:	79/491 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RINLAIMLFMACLLSYMMRVNLSINIIAMV----ED----------------TSSHENG------ 50
            |:..||..|:|..|...||..|.:.|:.||    ||                ||:...|
  Fly    27 RLTYAICAFLATCLHAAMRNMLGMIILKMVMPRPEDALVVPAGLSRLTEGNVTSTGRCGSPRVVF 91

  Fly    51 ------TEVEALPDYGPRYNWTQSDQALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAG 109
                  |:...||       ||::.:....|.|:|||:::...:|.||:...::.:...|.:...
  Fly    92 NPQIQETQSGDLP-------WTRNQELTFPGVYYYGYVVSISLSGYLADRCSSKRLFIVSLIFEA 149

  Fly   110 ILTALTPAAAAWDKYAVFAVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGKFVASLMGG-TFGTVI 173
            :...|.||.|.....|......:.|.|.|...|..:.|...|:.|.|:...::....| ..|:::
  Fly   150 VAYILLPAMAHSSFEAGVVDLVICGLLAGCGNPAMYKLFVTWAHPTERTALLSFAYSGLLMGSML 214

  Fly   174 TWPISGVIIENLGWDWAFYIVGIFVLVVVAIWFYLVADTPAQHSTISLKEREYI---ESSLGDTL 235
            .:|::. .:.|.||:.:||:||...|.......:||.||..||..||.:|.:|:   :|.||
  Fly   215 VYPVAS-YLSNFGWELSFYVVGGVGLSFGIACCFLVYDTVEQHPRISNEEVDYLRQGKSQLG--- 275

  Fly   236 SNKKKWP----PYKELVLSLPFWSLMMLHYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLP 296
              :::.|    |:|.|:.:.|.::.::.|....:....::...|:|:.|.:.|:|...||||:.|
  Fly   276 --QQRQPVVTIPWKSLLAAPPVYAFILTHMFHTYTFLVIVQLMPRFMREAMEFDLREVGFLSAAP 338

  Fly   297 HV----ARLLCAFGFGAVADWIRRR---GWLSVTRMRKAFCLPSHILPGVMLIILAYFGRDPYVC 354
            ::    ::::|..|    ..::.||   ....|.||....|   .||...::.::.....|..:.
  Fly   339 YLGGICSKVMCILG----GSYVERRVGPDQNCVRRMLYGIC---SILTTSLIGVIILANCDDKIL 396

  Fly   355 VAIM------TISLGFNGAATASNLANSQDLAPNYAGTLYGIINCVGTTPGIFSPLIVAAFTKNE 413
            |.:|      |..:||:|     ........||::||.|.|:.|.:....|..:|.:|||.. :.
  Fly   397 VLVMFAFMMATTDMGFSG-----YWPTLLYFAPSFAGLLSGLANGMAHLSGFLAPHLVAALV-HT 455

  Fly   414 NTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWN 449
            .:.|:|:.|.:.......:..|.|....|..:|.|:
  Fly   456 GSKDEWNVVLMTLIVFNTMAMLVFAFCSSTNLQPWD 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	121/491 (25%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	100/405 (25%)
CG7091	NP_650243.2	2A0114euk	77..498	CDD:129972	107/441 (24%)
CG7091	NP_650243.2	MFS	115..482	CDD:119392	96/385 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46770
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.980