DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9864 and CG3649

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	127/457 - (27%)
Similarity:	230/457 - (50%)	Gaps:	32/457 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IMLFMACLLSYMMRVNLSINIIAMVEDTSSHENGTEVEALPDYGPRYNWTQSDQALLLGAYFYGY 81
            :.||:...|....|.|:|:.|:|.....||:         |:| |.|..|:..::..:.:.|:|.
  Fly    23 LFLFLCATLIVAQRFNMSVAIVAFTNANSSN---------PNY-PEYRLTEPQKSYTISSPFWGS 77

  Fly    82 MITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKY-AVFAVRFLIGFLNGVVYPCCH 145
            ..|.:.:|.|:...||:.:.....|:..:|:..||.|.||..: .:|.|||:.|...|.::||.:
  Fly    78 CCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLY 142

  Fly   146 SLVSKWSPPDEKGKFVASLMGGTF------GTVITWPISGVIIEN-LGWDWAFYIVGIFVLVVVA 203
            :.::||.|..|     |:.|||..      ||::.:.:|||:..: |||...||:.|...:|...
  Fly   143 THLAKWCPKKE-----ANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCL 202

  Fly   204 IWFYLVADTPAQHSTISLKEREYIESSLGDTLSNKKKWP--PYKELVLSLPFWSLMMLHYGSMWG 266
            .:....|::|::...|||.||::|:.:|......:...|  |:.:::.|.||..|..........
  Fly   203 TFLRYGANSPSESKFISLAERKHIQFALEQNQVIRGATPPVPWLQILTSRPFIVLAFCKMSQACS 267

  Fly   267 LFFLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFGAVADWIRRRGWLSVTRMRKAFCL 331
            .:.|:...|:::..:..:::::...||:||.|..|:.::||..:|:::.||..:|:..:||....
  Fly   268 FYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPILRKTINS 332

  Fly   332 PSHILPGVMLIILAYFGRDPYV----CVAIMTISLGFNGAATASNLANSQDLAPNYAGTLYGIIN 392
            .:...|.|.|:||:|......|    |:...|.::  :|.|..|:| |..||:||:||.|:|:.|
  Fly   333 FATWTPAVALVILSYVSDQNVVGSMFCLIAATAAI--SGQAIGSSL-NHVDLSPNFAGLLFGMSN 394

  Fly   393 CVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWNEVQTTESR 457
            .:.:..|:.||:::......|:...||..||:..:....|..|.:.:||...:|.||:..:.|:.
  Fly   395 TLMSAAGVISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWNDSPSKETE 459

  Fly   458 ED 459
            .:
  Fly   460 TE 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	126/450 (28%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	111/398 (28%)
CG3649	NP_611725.2	MFS	22..442	CDD:119392	121/436 (28%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	126/452 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970