DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and CG12490

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	134/458 - (29%)
Similarity:	233/458 - (50%)	Gaps:	27/458 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AIMLFMACLLSYMMRVNLSINIIAMVEDTSSHENGTEVEALPDYGPRYNWTQSDQALLLGAYFYG 80
            |:::|:.....::.|:|:.::::||....:::.|          .|.|:||:::::.:..::|:|
  Fly    18 ALLIFLNITTVFIGRLNVGVSVVAMTNAETTNPN----------FPEYDWTEAEKSYIFSSFFWG 72

  Fly    81 YMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTP---AAAAWDKYAVFAVRFLIGFLNGVVYP 142
            |::|....|.|.:..|.::|..:...|:|:.:||||   ....|..|.  .:|.::|...|:|:|
  Fly    73 YILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAYC--GIRVVMGLAQGLVFP 135

  Fly   143 CCHSLVSKWSPPDEKGKFVA-SLMGGTFGTVITWPISGVIIEN-LGWDWAFYIVGIFVLVVVAIW 205
            |.|..::|||||.|:.:..| |..|...|.|....:||:|.:: :||....|:.........|||
  Fly   136 CIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAIGWPGISYVSAGLAFAWCAIW 200

  Fly   206 FYLVADTPAQHSTISLKEREYIESSLGDTLS-NKKKWP-PYKELVLSLPFWSLMMLHYGSMWGLF 268
            |...||...:...|:.:|..||||||..... :|...| |:..:..|.||.:|.:....:.|||.
  Fly   201 FVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVIPVPWMAIWTSAPFLALTLTRCCATWGLS 265

  Fly   269 FLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFGAVADWIRRRGWLSVTRMRKAFCLPS 333
            .|....|.:::.||..::.|..|.|:||.:|..:.::.:..:||.:.....||:|.:||.|...:
  Fly   266 TLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKTFNSLA 330

  Fly   334 HILPGVMLIILAYFGRD-PYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGTLYGIINCVGTT 397
            ..:|...||.:.:..:: ..:.:|:||||:|.|..||..:..|:.||:||:|..|.||:|...|.
  Fly   331 FWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGILNTAVTV 395

  Fly   398 PGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWNEVQTTESREDIVN 462
            ..|.:||||......::...:|..||||.|..:.:....:..||:...|.|:       .||.:.
  Fly   396 VPIVTPLIVGVIVHEDDNRAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQPWD-------AEDYLT 453

  Fly   463 TKL 465
            .|:
  Fly   454 VKV 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	131/445 (29%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	120/392 (31%)
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	131/450 (29%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	119/385 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.960