DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and Slc17a8

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_714947.1	Gene:	Slc17a8 / 266767	RGDID:	628870	Length:	588	Species:	Rattus norvegicus

Alignment Length:	463	Identity:	147/463 - (31%)
Similarity:	256/463 - (55%)	Gaps:	13/463 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CFYVPKRINLAIMLFMACLLSYMMRVNLSINIIAMVEDTSSHENG-TEVEALPDYGPRYNWTQSD 69
            |..:|||..:|:|..:...:|:.:|.||.:.|:.||.:::.:.:| .|::.     .::||....
  Rat    69 CCGIPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQT-----AQFNWDPET 128

  Fly    70 QALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKYAVFAVRFLIG 134
            ..|:.|::|:||::|.:|.|.::....|..|.|.:..:...|....|:||......|..||.|.|
  Rat   129 VGLIHGSFFWGYIVTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVRILQG 193

  Fly   135 FLNGVVYPCCHSLVSKWSPPDEKGKFVASLMGGTF-GTVITWPISGVIIENLGWDWAFYIVGIFV 198
            .:.||.||.||.:.|||:||.|:.:...:...|:: |.|:..|::||:::.:||...|||.|:|.
  Rat   194 LVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASVFYIYGMFG 258

  Fly   199 LVVVAIWFYLVADTPAQHSTISLKEREYIESSLGD--TLSNKKKW-PPYKELVLSLPFWSLMMLH 260
            ::....|.....:.||.|.|||.:||.|||:|:|:  .|::..|: .|::....|||.:::::.:
  Rat   259 IIWYMFWLLQAYECPAVHPTISNEERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVAN 323

  Fly   261 YGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFGAVADWIRRRGWLSVTRM 325
            :...|..:.|:.:.|.:..||.||.:|..|.||::||:...:.....|.:||::|.|..|:.|.:
  Rat   324 FCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAV 388

  Fly   326 RKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGTLYGI 390
            ||........:...:|:::. |.....|.::.:.:::||:|.|.:....|..|:||.||..|.||
  Rat   389 RKIMNCGGFGMEATLLLVVG-FSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGI 452

  Fly   391 INCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWNEVQT-T 454
            .|.|||..|:..||||.|.||:: |.::|..||:|.|..:....:|:.||.||:.|.|.:.:. :
  Rat   453 SNGVGTLSGMVCPLIVGAMTKHK-TREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLS 516

  Fly   455 ESREDIVN 462
            |.:..|::
  Rat   517 EEKCGIID 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	145/453 (32%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	124/388 (32%)
Slc17a8	NP_714947.1	MFS_SLC17A6_7_8_VGluT	79..502	CDD:340940	136/429 (32%)
Slc17a8	NP_714947.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	539..588
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820