DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and Slc17a3

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_006254003.1	Gene:	Slc17a3 / 266730	RGDID:	628815	Length:	538	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	139/466 - (29%)
Similarity:	220/466 - (47%)	Gaps:	25/466 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PCFYVPKRINLAIML-FMACLLSYMMRVN---LSINIIAMVEDT-------SSHE------NGTE 52
            |.|.:|...::...: |:|.:.::.:...   :||.::|||.:|       ||.|      ||.:
  Rat    67 PKFTIPSLCSMRYSIAFIAHICNFTLIAQNSIISITMVAMVNNTDQPSHLNSSTEWFPDGLNGDQ 131

  Fly    53 VEA---LPDYGPRYNWTQSDQALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTAL 114
            .||   |....|.|||:...|.::..:..||.|:...|.|.||..||.:.|.|.:.|.:.:||..
  Rat   132 HEASKHLSIKAPVYNWSPQTQGIIFSSVQYGMMLMQGPGGYLAGKLGTKKVVGIALLGSSLLTLC 196

  Fly   115 TPAAAAWDKYAVFAVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGKFVASLMGG-TFGTVITWPIS 178
            .|.||......:.|.|.:.|...|..|....:|..||:||:|:.:..:..|.| ..|......:.
  Rat   197 IPLAANLGLAFLLATRAVQGLTQGAGYGGQFALWQKWAPPNERSRLCSIAMSGMILGIFAVLLVG 261

  Fly   179 GVIIENLGWDWAFYIVGIFVLVVVAIWFYLVADTPAQHSTISLKEREYIESSLGDTLSNKKKWPP 243
            |:|.|.|||.:.|||.|...:|...:|..||.|.|..|..||..|:|||.|||....:::::..|
  Rat   262 GIISEALGWPFVFYIFGSIGVVCCLLWLILVYDDPVSHPWISSPEKEYILSSLDQQFNSEEQPLP 326

  Fly   244 YKELVLSLPFWSLMMLHYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLP-HVARLLCAFGF 307
            .|.::.|||.||:.:......|.:..||..||.::|.|...|:...|.||||| .||.::...|
  Rat   327 IKAMLKSLPLWSMCLCSMTHQWLVNTLIIYTPTYISSVFKVNIRDNGLLSSLPFFVAWVIGILG- 390

  Fly   308 GAVADWIRRRGWLSVTRMRKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAATASN 372
            |.:||::..:.:..:| :||...:..:..|..:::.|.|...........:|:|.|.:....:..
  Rat   391 GLLADFLLSKNFRLIT-VRKIITILGNTPPAALVVALPYVQSSYIATTTFLTLSCGLSPLCQSGV 454

  Fly   373 LANSQDLAPNYAGTLYGIINCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFF 437
            ..|:.|:||.||..|.|....:..:..:..| |||.|..|:::...|...|.:..|..:...:.:
  Rat   455 YINALDIAPRYASLLMGTSRGLAHSSAVMVP-IVAGFFLNQDSEFGWRNFFFVLFAINLFGLIIY 518

  Fly   438 WVFGSGKIQKW 448
            .||....||:|
  Rat   519 LVFAKADIQEW 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	139/466 (30%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	117/389 (30%)
Slc17a3	XP_006254003.1	2A0114euk	71..537	CDD:129972	137/462 (30%)
Slc17a3	XP_006254003.1	MFS	145..522	CDD:119392	115/379 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820