DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9864 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	495	Identity:	91/495 - (18%)
Similarity:	184/495 - (37%)	Gaps:	145/495 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VPKRINLAIMLFMA------CLLSYMMRVNLSINIIAMVEDTSSHENGTEVEALPDYGPRYNWTQ 67
            |.|::.|.:.|.::      .|::::.|.|:....:|.:           .|||..||.|.|
pombe    49 VEKKLLLKMDLVISPIIGFLYLMAFLDRSNIGNAAVAGM-----------TEALSLYGERLN--- 99

  Fly    68 SDQALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKYAVF----- 127
                :.:..::..|::...|:..|.:.:.|..:..:             .:.||....:|
pombe   100 ----VAVSIFYVLYILVETPSVVLVKRIKASRMLAF-------------ISFAWSMTVLFSGFMS 147

  Fly   128 ------AVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGK-----FVASLMGGTFGTVITWPISGVI 181
                  |.|.::|.|.|.::|..:..::......|:.:     |.::.:.|.||.:..:.:..|.
pombe   148 SYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVH 212

  Fly   182 IENL-GWDWAFYIVGIFVLVVVAIWFYLVADTPAQHSTISLKERE--YIESSLGDTLSNKK--KW 241
            ..|. ||.|.:.:.|:...:.|.:..:.:.|.......::.:|||  .|...:......::  :|
pombe   213 AGNKEGWQWIYIVEGLVSFIGVPLCLFALPDKMENAWFLTREEREVAIIRRDINARYHGEQHFEW 277

  Fly   242 PPYKELVLSLPFWSLMMLHYGSMWGLFFLITATPKFLSEVLGFNLSS--------AGFLS----- 293
            ...::.......:                ::||.:|.::::.:..||        .||:.
pombe   278 SEVRKAFKDPKVY----------------VSATSQFCADMVLYGFSSFLPVIIKGLGFVGLQTNY 326

  Fly   294 -SLPHVARLLCAFGFGAVADWIRRRGWLS-VTRMRKAFCLPSH--ILPGVMLIILAYFGRDPYVC 354
             ::|.....:.:|.|.|         ||| .|::|..:.:.:.  :..|.::::.:......|..
pombe   327 MTIPVYIAGVISFLFVA---------WLSDRTQLRAVYLISASTVVAVGYIIMLASDSNAAKYTA 382

  Fly   355 VAIMTI--------SLGF---NGA-----ATA----SNLANSQDLAPNYAGTLYGIINCVGTTPG 399
            ..|:.|        :||:   |.|     |||    ..||||..:.   ||.:|...|
pombe   383 TYIIAIGCYIGPGLNLGWLNNNVAGHYKRATAIGIQQTLANSSGIV---AGQIYRSKN------- 437

  Fly   400 IFSP--LIVAAFTKNENTIDQWHWVFIIGAAAYILPALFF 437
              :|  ::..|||..         ..|:|..||::  :||
pombe   438 --APKYILGNAFTLG---------CVIVGGLAYVV--MFF 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	91/495 (18%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	82/443 (19%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	85/469 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050