DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and Slc17a5

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_766361.1	Gene:	Slc17a5 / 235504	MGIID:	1924105	Length:	495	Species:	Mus musculus

Alignment Length:	449	Identity:	163/449 - (36%)
Similarity:	248/449 - (55%)	Gaps:	14/449 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RINLAIMLFMACLLSYMMRVNLSINIIAMVE-DTSSHENGTEVEALPDYGP----------RYNW 65
            |.||||:.|....:.|.:|||||:.::.||: :|:..:|.|..|......|          :|.|
Mouse    39 RYNLAILAFCGFFVLYALRVNLSVALVDMVDSNTTLTDNRTSKECAEHSAPIKVHHNHTGKKYKW 103

  Fly    66 TQSDQALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKYAVFAVR 130
            ....|..:||::||||::|.:|.|.:|..:|.:.:.|...|...:.|..||.||......:..:|
Mouse   104 DAETQGWILGSFFYGYIVTQIPGGYIASRVGGKLLLGLGILGTSVFTLFTPLAADLGVVTLVVLR 168

  Fly   131 FLIGFLNGVVYPCCHSLVSKWSPPDEKGKFVA-SLMGGTFGTVITWPISGVIIENLGWDWAFYIV 194
            .|.|...||.:|..|::.|.|:||.|:.|.:. |..|...||||:.|:||:|...:.|.:.||:.
Mouse   169 ALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGIICYYMNWTYVFYLF 233

  Fly   195 GIFVLVVVAIWFYLVADTPAQHSTISLKEREYIESSLGDTLSNKKKWPPYKELVLSLPFWSLMML 259
            ||..:|...:|.::|:|||..|.|||..|:|||.|||.:.||::|. .|:..::.|||.|::::.
Mouse   234 GIVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSLKNQLSSQKV-VPWGSILKSLPLWAIVVA 297

  Fly   260 HYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFGAVADWIRRRGWLSVTR 324
            |:...|..:.|:|..|.::.|:|.||:...||||:||:....||....|..||::|.:...|...
Mouse   298 HFSYNWSFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMILCGQAADYLRVKWNFSTIS 362

  Fly   325 MRKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGTLYG 389
            :|:.|.|...:.|.|.|:...:.|.|..:.||.:|||....|.|::....|..|:||:|||.|.|
Mouse   363 VRRIFSLVGMVGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFASSGFSINHLDIAPSYAGILLG 427

  Fly   390 IINCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKW 448
            |.|...|.||:..|:|..:.|. :|||.:|..||.|.||..:..|:||.:|..|::|.|
Mouse   428 ITNTFATIPGMTGPIIAKSLTP-DNTIREWQTVFCIAAAINVFGAIFFTLFAKGEVQSW 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	163/449 (36%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	141/395 (36%)
Slc17a5	NP_766361.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
		Dileucine internalization motif. /evidence=ECO:0000250	22..23
		2A0114euk	30..491	CDD:129972	163/449 (36%)
		MFS	99..478	CDD:119392	140/380 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910