DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and slc-17.4

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_503071.2	Gene:	slc-17.4 / 189054	WormBaseID:	WBGene00012130	Length:	573	Species:	Caenorhabditis elegans

Alignment Length:	510	Identity:	108/510 - (21%)
Similarity:	221/510 - (43%)	Gaps:	64/510 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FYVP--KRINLAIMLFMACLLSYMMRVNLSINIIAMVEDTS----------SHENGTEV------ 53
            |:.|  :|:::.::.......:..||::::|::..|:..|:          :.||.:.:
Worm    23 FFHPFSRRLHICLLCMAGFCCTTFMRMHIAISMTCMINSTALALESAVFPEAFENSSSIFEELEP 87

  Fly    54 --------------EALPDYGPRYNWTQSDQALLLGAYFYGYMITSLPAGTLAEMLGARNV--AG 102
                          :.:.|||.:..|...:|.|:....|:|.:||.||:.........|.|  |.
Worm    88 VSNGACSSNADVNKKVVVDYGGQLVWNSQEQNLIFSGTFWGSIITVLPSMFFINRYSPRYVLQAA 152

  Fly   103 YSCLVAGILTALTP-AAAAWDKYAVFAVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGKFVA---- 162
            ..|.:  ::||:|| .|..:..|.||..|.::|...|.:.|..:::::.|.|..|:...::
Worm   153 VGCYI--LMTAITPYIATRFGPYPVFISRVIMGLGEGFILPANNAILANWFPSAERSTAISLFTT 215

  Fly   163 -SLMGGTFGTVITWPISGVIIENLGWDWAFYIVGIFVLVVVAIWFYLVADTPAQHSTISLKEREY 226
             :.|.|..|..:.   :.:...:.||...||...|...:....||...::.|::...::..||:|
Worm   216 GNQMAGAGGNPVA---ASLCASSFGWPSIFYFASIVSTIWSVCWFLTASNQPSKCKVMTKTERDY 277

  Fly   227 IESSL--GDTLSNKKKWPPYKELVLSLPFWSLMMLHYGSMWGLFFLITA----TPKFLSEVLGFN 285
            :::::  ....:|:....||.:::.|..|.:.::..:    .:.|::|.    .|.:..:||...
Worm   278 LDANVVRRSNKTNRSLVVPYSKILKSPAFLAQLLCQF----VINFIVTLLQIYLPNYFKDVLHLG 338

  Fly   286 LSSAGFLSSLPHVARLLCAFGFGAVADWIRRRGWLSVTRMRKAFCLPSHILPGVMLIILAYF--G 348
            :.:.|..:|:|::........:|...|..:.:..:|.|...|.....::....:.||::.||  .
Worm   339 VIANGTYTSVPNIVNFALKIVWGITIDRAKEKKIISGTFGVKLSQSIANFGGALFLILITYFVDC 403

  Fly   349 RDPYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGTLYGIINCVGTTPGIFSPLIVAAFTKNE 413
            .:|.:......:..|..|...:....:...|||.|..|:..|.........:.:|.|| ...|.:
Worm   404 TNPTLGFVFFCMMYGCMGTLVSGFYTSLLSLAPKYTATMSSISVFCAMMGRLATPAIV-GLIKKQ 467

  Fly   414 NTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKW------NEVQTTESREDIVN 462
            ||:.:|..:|::.|||.|:....|.|||||::|:|      .|::|...:..:.:
Worm   468 NTLSEWQTLFLVCAAANIICGAVFLVFGSGELQEWGLEDEAKEMKTLAEKTPLAS 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	107/500 (21%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	89/400 (22%)
slc-17.4	NP_503071.2	MFS	34..495	CDD:391944	97/470 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020