DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and slc-17.9

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001379067.1	Gene:	slc-17.9 / 181189	WormBaseID:	WBGene00011643	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	494	Identity:	128/494 - (25%)
Similarity:	221/494 - (44%)	Gaps:	49/494 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CFYVPKRINL-----AIMLFMACLLSYMMRV---NLSINIIAMVE--DTSSHENGT------EVE 54
            |.:|.::..:     ....|:.||....:.:   |:|.:::.||:  ||    |.|      |||
Worm     7 CVFVSEKSKIFPSTRLFFSFLLCLCFVALAIGTSNISQSMVCMVKKPDT----NYTCPLAEPEVE 67

  Fly    55 ALPDYGPR-YNWTQSDQALLLGAYFYG--YMITSLPAGTLAEMLGAR--NVAGYSCLVAGILTAL 114
            |:|...|: :.|:...|.|:.....:|  :|:.:   |..|:.|..:  .||..:.::  :..|:
Worm    68 AIPCNHPKQFAWSSIQQGLIYSGQNFGSLFMVIT---GWQADRLNGKWTIVAAMAFII--VSNAV 127

  Fly   115 TPAAAAWDKYAVFAVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGKFVASLMGG-TFGTVITWPIS 178
            .|.:|......||.:|.|.||.:.::.|...||:::|.||.|:...:..:..| ..||:|..||.
Worm   128 LPISAGASFALVFFLRVLTGFGDALLSPASSSLITRWFPPKERPSALGIVTSGRQIGTLIILPIG 192

  Fly   179 GVIIEN------LGWDWAFYIVGIFVLVVVAIWFYLVADTPAQHSTISLKEREYI-----ESSLG 232
            |.:..:      .||...||:..:....|:.||....||.|::|..||..|..||     |.::|
Worm   193 GWLCGSDGSKFLGGWPAIFYLSSVVAAAVLVIWVVFSADKPSKHLCISHNEEAYINRKIEEENIG 257

  Fly   233 DTLSNKKKWPPYKELVLSLPFWSLMMLHYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPH 297
            .  .|.:|..|:|.:..|...|..:.......:.|..::...|||.|:|||.:.:..|.:|:||.
Worm   258 K--RNNRKNTPWKAIFTSKQVWVAVAALVCHEFPLVIMLQFLPKFFSDVLGLSNTVNGLVSALPM 320

  Fly   298 VARLLCAFGFGAVADWIRRRGWLSVTRMRKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISL 362
            ....|......::|.::...|:|..|:..|.|...:.:..|:.:..........:...||:.:.|
Worm   321 AILFLSKCLSASLASYLTANGYLRKTQSCKIFNFIASLGLGICIAATPLMSNLQHAIWAIIILCL 385

  Fly   363 --GFNGAATASNLANSQDLAPNYAGTLYGIINCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFII 425
              .|.|..|...|.....|||.::|.:.|:...|.:...||:.|:::...:. .:..:|..||.|
Worm   386 ANAFAGLHTPGVLTAIVQLAPAFSGIITGLAFAVASCFSIFNKLLISQILRT-GSKHEWTIVFEI 449

  Fly   426 GAAAYILPALFFWVFGSGKIQKW--NEVQTTESREDIVN 462
            .|...|||.:||.::||.:..:|  |.|...:..:...|
Worm   450 SAFVAILPTIFFTLWGSAERTEWASNRVSVPKDADQKSN 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	127/484 (26%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	106/403 (26%)
slc-17.9	NP_001379067.1	2A0114euk	5..474	CDD:129972	125/478 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910