DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and eat-4

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_499023.3	Gene:	eat-4 / 176291	WormBaseID:	WBGene00001135	Length:	576	Species:	Caenorhabditis elegans

Alignment Length:	463	Identity:	132/463 - (28%)
Similarity:	230/463 - (49%)	Gaps:	26/463 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KRINLAIMLFMACLLSYMMRVNLSINIIAMVEDTSSHENGTEVEALPDYGP----RYNWTQSDQA 71
            ||..|||:..|..::|:.:|.|..      ...|..::|.|:     .||.    .:|||..:.:
Worm    68 KRWLLAILANMGFMISFGIRCNFG------AAKTHMYKNYTD-----PYGKVHMHEFNWTIDELS 121

  Fly    72 LLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTP-AAAAWDKYAVFAVRFLIGF 135
            ::..:|||||::|.:|||.||.......:.|:...|...|..|.| .......|.|..::...|.
Worm   122 VMESSYFYGYLVTQIPAGFLAAKFPPNKLFGFGIGVGAFLNILLPYGFKVKSDYLVAFIQITQGL 186

  Fly   136 LNGVVYPCCHSLVSKWSPPDEKGKFVASLMGGTF-GTVITWPISGVIIENLGWDWAFYIVGIFVL 199
            :.||.||..|.:...|:||.|:.|...:...|:: |.|:..|:|..::..:.|...||:.|:..:
Worm   187 VQGVCYPAMHGVWRYWAPPMERSKLATTAFTGSYAGAVLGLPLSAFLVSYVSWAAPFYLYGVCGV 251

  Fly   200 VVVAIWFYLVADTPAQHSTISLKEREYIESSLGDTLSNKK---KWPPYKELVLSLPFWSLMMLHY 261
            :...:||.:..:.||.|.|||.:|:.:||.::|. :||..   :..|:|.:|.|.|.|::::.::
Worm   252 IWAILWFCVTFEKPAFHPTISQEEKIFIEDAIGH-VSNTHPTIRSIPWKAIVTSKPVWAIIVANF 315

  Fly   262 GSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFGAVADWIRRRGWLSVTRMR 326
            ...|..:.|:.....::.|.||..::.:|.|:::||:.........|.:||::|....||.|.:|
Worm   316 ARSWTFYLLLQNQLTYMKEALGMKIADSGLLAAIPHLVMGCVVLMGGQLADYLRSNKILSTTAVR 380

  Fly   327 KAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGTLYGII 391
            |.|...........::|:||...|....:|::. ::|.:|.|.:....|..|:||.||..|.|..
Worm   381 KIFNCGGFGGEAAFMLIVAYTTSDTTAIMALIA-AVGMSGFAISGFNVNHLDIAPRYAAILMGFS 444

  Fly   392 NCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWNEVQTTE- 455
            |.:||..|:..|.:..|||.:..  ..|..||::.:..:.....|:.|:.||::|:|.|.:..|
Worm   445 NGIGTLAGLTCPFVTEAFTAHSK--HGWTSVFLLASLIHFTGVTFYAVYASGELQEWAEPKEEEE 507

  Fly   456 -SREDIVN 462
             |.:::||
Worm   508 WSNKELVN 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	128/451 (28%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	110/393 (28%)
eat-4	NP_499023.3	2A0114euk	66..497	CDD:129972	125/443 (28%)
eat-4	NP_499023.3	MFS	110..492	CDD:119392	109/385 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920