DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and slc-17.6

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_490947.2	Gene:	slc-17.6 / 171781	WormBaseID:	WBGene00017398	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	465	Identity:	115/465 - (24%)
Similarity:	200/465 - (43%)	Gaps:	38/465 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RINLAIMLFMACLLSYMMRVNLSINIIAMVEDTSSHENGTEVEALPDYGPRYNWTQSDQALLLGA 76
            |...|:::..||::..:||....   :|||:...| .|||   ..||.  ...|:..:||.:..:
Worm    26 RFQTALLISAACVVFGLMRTCFG---MAMVDIVRS-GNGT---FHPDL--HMEWSGDEQANIHTS 81

  Fly    77 YFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAW--DKYAVFAVRFLIGFLNGV 139
            ::.|..|...|:..||:.||.:|:..::.|:....:.|||.:|.:  ..:.|.|:|.::||..|.
Worm    82 FYIGAFIAVFPSEFLAKKLGPKNLLSFALLLNIFGSLLTPFSAIYLRSYFPVAAIRLIMGFGYGF 146

  Fly   140 VYPCCHSLVSKWSPPDEKGKFVASLMGGTFGTVITWPISGVIIENL-------GWDWAFYIVGIF 197
            |.|....|:|.|.|..||...:|..   |.|..|...:|..:...|       ||...|.:.|:.
Worm   147 VIPAGSVLISSWFPLSEKSTAMAIF---TTGNQIGIAVSMFLTAKLCQLHFFEGWPLVFIVYGLI 208

  Fly   198 VLVVVAIWFYLVADTPAQHSTISLKEREYIESSLGDTLSNKK----KWPPYKELVLSLPFWSLMM 258
            ..|.:.||...:||.|.:...|:..|..||:.  |....|:.    :..||.:::|:....::..
Worm   209 GAVFLVIWHVRLADKPRESKYITATELTYIKG--GKQRRNRAETIVRATPYMKIILNGCVCAICA 271

  Fly   259 LHYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFGAVADWIRRR--GWLS 321
            ..:...:.|..|:|..||:.......||:..|..||||...:::....|..:||.:::|  ...:
Worm   272 CSFAQSFVLVALVTYLPKYNQIAFKMNLTHNGIWSSLPFFIQMITKLLFAIIADKVKQRKVNATA 336

  Fly   322 VTRMRKAFCLPSHILPGVMLIILAY--FGRDPYVCVAIMTISLGFNGAATASNLANSQDLAPNYA 384
            ||::..|.   :.....:.::|.||  |.....|.::|:.....|:......| .:...:||.:.
Worm   337 VTKVSNAI---ASFASAIFIVIAAYGPFDSAELVQLSIIVSMAAFSAYVPGYN-TSIVTVAPQFT 397

  Fly   385 GTLYGIINCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWN 449
            ..:..............:|:::...| :..||.:|...|...|....:..|.|.:||.|:.:.|.
Worm   398 AFISSYAQLYAQIASTLAPIVIGRIT-SHGTIYEWKCAFYSLAGVLAVTGLIFQIFGHGRTEPWG 461

  Fly   450 EV--QTTESR 457
            |.  ..|.:|
Worm   462 ETPSNATSAR 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	113/460 (25%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	95/401 (24%)
slc-17.6	NP_490947.2	MFS	30..453	CDD:391944	107/441 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010