DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9864 and Slc17a1

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	462	Identity:	140/462 - (30%)
Similarity:	221/462 - (47%)	Gaps:	20/462 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VPKRI--------NLAIMLFMACLLSYMMRVNLSINIIAMVEDTS-SHENGTEVEALPD--YGPR 62
            :||::        .|||:|....::....||.|::.::|||..|. .|.:...|..:.|  ..|.
  Rat     6 LPKKVPGFCSFRYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPV 70

  Fly    63 YNWTQSDQALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKYAVF 127
            ::|:...|.|:|.:.|.|.::..:|.|.|:.....:.:.|.|..::.:|:.|.|.||......|.
  Rat    71 HSWSLDIQGLILSSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIPPAAQVGAALVI 135

  Fly   128 AVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGKFVA-SLMGGTFGTVITWPISGVIIENLGWDWAF 191
            ..|.|.|...|.|....|.:..||:||.|:|:..: :|.|...|..|...:||.|.:.|||...|
  Rat   136 VCRVLQGIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFICDLLGWPMVF 200

  Fly   192 YIVGIFVLVVVAIWFYLVADTPAQHSTISLKEREYIESSLGDTLSNKKKWPPYKELVLSLPFWSL 256
            ||.||...|:...||.|..|.|..|..:|..|::||.|||...:.:.::..|.|.::.|||.|::
  Rat   201 YIFGIVGCVLSLFWFILFFDDPNNHPYMSSSEKDYITSSLMQQVHSGRQSLPIKAMLKSLPLWAI 265

  Fly   257 MMLHYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPHVARLLCAFGFGAVADWIRRRGWLS 321
            ::..:..:|....|:|.||.|:|..|..|:...|.|||||::...:|....|.::|::..|...|
  Rat   266 ILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKIFS 330

  Fly   322 VTRMRKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGT 386
            |..:||.|.......|.:.::.|.|...:.|..|..:|::......:....|.|:.|:||.|
  Rat   331 VVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTVIFLTLANSTLSFSFCGQLINALDIAPRY--- 392

  Fly   387 LYGIINCVGTTPGIFSPLI---VAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKW 448
             ||.:..|....|||..||   :|....|::....||..|.:.|...:....|:.:|..|.||.|
  Rat   393 -YGFLKAVTALIGIFGGLISSTLAGLILNQDPEYAWHKNFFLMAGINVTCLAFYLLFAKGDIQDW 456

  Fly   449 -NEVQTT 454
             .|.:||
  Rat   457 AKETKTT 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	138/460 (30%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	117/390 (30%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	140/462 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910