DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_038966881.1	Gene:	Slc17a7 / 116638	RGDID:	620101	Length:	585	Species:	Rattus norvegicus

Alignment Length:	472	Identity:	150/472 - (31%)
Similarity:	257/472 - (54%)	Gaps:	30/472 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CFYVPKRINLAIMLFMACLLSYMMRVNLSINIIAMVEDTSSHENGTEV-----------EAL-PD 58
            ||.:|:|..:|||..:...:|:.:|.||.:.|::||.::::|..|..|           ||: |.
  Rat    56 CFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQTPYRSVHKQEAVTPT 120

  Fly    59 YG---------PRYNWTQSDQALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTAL 114
            .|         .::||......|:.|::|:||::|.:|.|.:.:...|..|.|::.:....|..|
  Rat   121 VGDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNML 185

  Fly   115 TPAAAAWDKYAVFAVRFLIGFLNGVVYPCCHSLVSKWSPPDEKGKFVASLMGGTF-GTVITWPIS 178
            .|:||......|..||.|.|.:.||.||.||.:.|||:||.|:.:...:...|:: |.|:..|::
  Rat   186 IPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLA 250

  Fly   179 GVIIENLGWDWAFYIVGIFVLVVVAIWFYLVADTPAQHSTISLKEREYIESSLGDT--LSN--KK 239
            ||:::..||...||:.|.|.:.....|..:..::||.|.:||.:||:|||.::|::  |.|  .|
  Rat   251 GVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPVTK 315

  Fly   240 KWPPYKELVLSLPFWSLMMLHYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPH-VARLLC 303
            ...|::....|:|.:::::.::...|..:.|:.:.|.:..||.||.:|..|.:|:||| |..::.
  Rat   316 FNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIV 380

  Fly   304 AFGFGAVADWIRRRGWLSVTRMRKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAA 368
            ..| |.:||::|.|..:|.|.:||........:...:|:::.| .....|.::.:.:::||:|.|
  Rat   381 PIG-GQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGY-SHSKGVAISFLVLAVGFSGFA 443

  Fly   369 TASNLANSQDLAPNYAGTLYGIINCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILP 433
            .:....|..|:||.||..|.||.|.|||..|:..|:||.|.||:: |.::|.:||:|.:..:...
  Rat   444 ISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHK-TREEWQYVFLIASLVHYGG 507

  Fly   434 ALFFWVFGSGKIQKWNE 450
            .:|:.||.||:.|.|.|
  Rat   508 VIFYGVFASGEKQPWAE 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	150/472 (32%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	125/400 (31%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	140/451 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920