DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9864 and slc17a6b

DIOPT Version :9

Sequence 1:	NP_001261100.1	Gene:	CG9864 / 37287	FlyBaseID:	FBgn0034490	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001122293.1	Gene:	slc17a6b / 100149756	ZFINID:	ZDB-GENE-030616-554	Length:	584	Species:	Danio rerio

Alignment Length:	460	Identity:	149/460 - (32%)
Similarity:	257/460 - (55%)	Gaps:	14/460 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CFYVPKRINLAIMLFMACLLSYMMRVNLSINIIAMVEDTSSHENGTEVEALPDYGPRYNWTQSDQ 70
            ||.:|:|..:|||..:...:|:.:|.||.:.|::||.:::.|.||   :.:.....::||.....
Zfish    63 CFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNG---KIIIKEKAKFNWDPETV 124

  Fly    71 ALLLGAYFYGYMITSLPAGTLAEMLGARNVAGYSCLVAGILTALTPAAAAWDKYAVFAVRFLIGF 135
            .|:.|::|:||::|.:|.|.::..|.|..|.|.:.|:...|....|:||......|..||.|.|.
Zfish   125 GLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYGCVIFVRILQGL 189

  Fly   136 LNGVVYPCCHSLVSKWSPPDEKGKFVASLMGGTF-GTVITWPISGVIIENLGWDWAFYIVGIFVL 199
            :.||.||.||.:.|||:||.|:.:...:...|:: |.||..|::|::::..||...||:.|.|.:
Zfish   190 VEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGCFGI 254

  Fly   200 VVVAIWFYLVADTPAQHSTISLKEREYIESSLGDTL-----SNKKKWPPYKELVLSLPFWSLMML 259
            .....|..:..::||:|.||:.:||.|||.|:|::.     ::|.| .|:::...|:|.:::::.
Zfish   255 FWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFK-TPWRKFFTSMPVYAIIVA 318

  Fly   260 HYGSMWGLFFLITATPKFLSEVLGFNLSSAGFLSSLPH-VARLLCAFGFGAVADWIRRRGWLSVT 323
            ::...|..:.|:.:.|.:..||.||.:|..|.||:||| |..::...| |.:||.:|.:..||.|
Zfish   319 NFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIG-GQLADHLRSKNILSTT 382

  Fly   324 RMRKAFCLPSHILPGVMLIILAYFGRDPYVCVAIMTISLGFNGAATASNLANSQDLAPNYAGTLY 388
            .:||........:...:|:|:.| .....|.::.:.:::||:|.|.:....|..|:||.||..|.
Zfish   383 TVRKIMNCGGFGMEATLLLIVGY-SHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILM 446

  Fly   389 GIINCVGTTPGIFSPLIVAAFTKNENTIDQWHWVFIIGAAAYILPALFFWVFGSGKIQKWNEVQT 453
            ||.|.|||..|:..||||.|.||:: |.::|.:||:|.:..:....:|:.:|.||:.|.|.:.:.
Zfish   447 GISNGVGTLSGMVCPLIVGAMTKHK-TREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWADPEL 510

  Fly   454 TESRE 458
            |...:
Zfish   511 TSDEK 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9864	NP_001261100.1	2A0114euk	4..454	CDD:129972	148/454 (33%)
CG9864	NP_001261100.1	MFS	55..440	CDD:119392	126/391 (32%)
slc17a6b	NP_001122293.1	2A0114euk	69..509	CDD:129972	145/446 (33%)
slc17a6b	NP_001122293.1	MFS	74..498	CDD:119392	138/430 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820