Protein Alignment ppk6 and ASIC3

DIOPT Version :9

• Sequence 1: NP_611461.3
• Gene: ppk6 / 37286
• FlyBaseID: FBgn0034489
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_064717.1
• Gene: ASIC3 / 9311
• HGNCID: 101
• Length: 549
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 96/480 - (20%)
• Similarity: 164/480 - (34%)
• Gaps: 121/480 - (25%)

  Fly    61 LSRFIWSSVLLQLLLLSIYLTLLLWLKFYSYPILNTISNDLSITDVAFPGVTICSPKVVNSERVD 125
            |.|.:|::.::..:...:| .:...:::|......|..::.....:.||.||:|:   :|..|..
Human    40 LRRGMWAAAVVLSVATFLY-QVAERVRYYREFHHQTALDERESHRLIFPAVTLCN---INPLRRS 100

  Fly   126 RYVKTLKIPKEYDMA-EVIAGFD------FLNAFTDQSFEPPGHDSYRATDAVLRLNNVSIWEAA 183
            |..     |.:...| ..:.|.|      ||.|. .:...|||
Human   101 RLT-----PNDLHWAGSALLGLDPAEHAAFLRAL-GRPPAPPG---------------------- 137

  Fly   184 MAVSPGCFD----YVKRCFWGHT--------EFQ---CNQSHEYLSFIPTTAYLGPCCSFNYNPR 233
            ...|| .||    |.:.   ||:        .|:   |...    :|......:|.|.:||....
Human   138 FMPSP-TFDMAQLYARA---GHSLDDMLLDCRFRGQPCGPE----NFTTIFTRMGKCYTFNSGAD 194

  Fly   234 NASFVPFSANIFGMDGGLTF-----------VGAEGSERNLNTGLIVLVHHPMD--YVTEAAASV 285
            .|..:..:..  ||..||..           |..:..|.....|:.|.:|...:  .:.:....|
Human   195 GAELLTTTRG--GMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPIIDQLGLGV 257

  Fly   286 T------ITAQSESFVEVSPTVQSSSVEVL--ELSERKRDCLISGDLQLS-NYRQAACLLACQTE 341
            :      ::.|.:....:.|.....|...|  .......|.|.|.....| .|....|.|||:|.
Human   258 SPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLGSPSPSPSPPYTLMGCRLACETR 322

  Fly   342 AIVKKCGCHPYLLPIVGNKFKECNLNDT-FCYSANYDNF------KSVRCDQC-LPN-CYDVTYS 397
            .:.:||||....:|           .|. .|....|.|.      ..:|.|.| .|| |     :
Human   323 YVARKCGCRMVYMP-----------GDVPVCSPQQYKNCAHPAIDAMLRKDSCACPNPC-----A 371

  Fly   398 TLSYKTDLNQHKY---SVSRFYSPELLNNDSFVLRVYLAKQV------VPVIRKVTVMSWIGLLS 453
            :..|..:|:..:.   :.:||.:.:|..:::::....||..:      ...:.:........||.
Human   372 STRYAKELSMVRIPSRAAARFLARKLNRSEAYIAENVLALDIFFEALNYETVEQKKAYEMSELLG 436

  Fly   454 DLGGIFNLCLGLSMISVVEFF-YYC 477
            |:||...|.:|.|:::::|.. |.|
Human   437 DIGGQMGLFIGASLLTILEILDYLC 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:279230	90/453 (20%)
ASIC3	NP_064717.1	ASC	20..534	CDD:295594	96/480 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..307		4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152120
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850