Protein Alignment ppk6 and scnn1b

DIOPT Version :10

• Sequence 1: NP_611461.3
• Gene: ppk6 / 37286
• FlyBaseID: FBgn0034489
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 114/554 - (20%)
• Similarity: 196/554 - (35%)
• Gaps: 157/554 - (28%)

  Fly    50 MWLMRRNRTYGLSRFIWSSV---LLQLLLLSIYLTLLLW------LKFYSYPILNTISNDLSITD 105
            :|......|:|..|.|....   ::..:|..::..|:.|      |.:.||.:  ::|..:....
 Frog    33 VWFCDNTNTHGPKRIIKEGPKKRVMWFILTLVFAGLVFWQWGVLILTYLSYGV--SVSLSIGFKT 95

  Fly   106 VAFPGVTICSPKVVNSERVDRYVKTLK--IPKEYDMAEVIAGFDFLNAFTDQS------FEP--- 159
            :.||.||:|:.......||...:|.|.  :....|..: .:..|..|.||..|      .:|
 Frog    96 MEFPAVTVCNANPYKYSRVKPLLKDLDALVATALDRIQ-FSSQDQANTFTQSSTNQNVTLDPTLW 159

  Fly   160 ---------------PGHDSYRATDAVLRLNN------------VSIWEAAMAVSPGCFDYVKRC 197
                           |..::....:|:...||            ...::.||.:   |.:...:|
 Frog   160 NHIPLVVIDETDPSNPIVNNIFDNNAIYSKNNSFRNSSEDQTSYSQRYKVAMKL---CTNNNTQC 221

  Fly   198 FWGH--------TEFQCNQSHEYLSFIP----------------TTAYLGPCCSFNYNPRNASFV 238
            .:.:        .|:...|.....|.:|                |..:.|..||:    ||.:
 Frog   222 VYRNFTSGIQALQEWYLLQLSSIFSNVPLADRIAMGFKAEDLILTCLFGGQPCSY----RNFT-- 280

  Fly   239 PFSANIFGMDGGLTFV---GAEGSE--RNLNTG------LIVLVHHP--MDYVTEAAASVTITAQ 290
                .|:..|.|..::   |.||.:  .:.|.|      |::.:...  :.||...||:..|..|
 Frog   281 ----RIYDADYGNCYIFNWGQEGEDPMASANPGADFGLKLVLDIEQGEYLPYVQTTAAARLILHQ 341

  Fly   291 SESF-------VEVSPTVQSSSVEVLELSERKR----DCLISG-DLQLSN--------YRQAACL 335
            ..||       :...|..::|...:::..|...    .|.::| |:.:.|        |...:||
 Frog   342 QRSFPFVKDLGIYAMPGTETSIAVLVDQLEHMEAPYSSCTVNGSDIPVQNLYAEFNSSYSIQSCL 406

  Fly   336 LACQTEAIVKKCGCHPYLLPIVGNKFKECNLNDTF-----CYSANYDNF--KSVRCDQCLPNCYD 393
            .:|..|.:|:.|||..|..|: .|..:.|: ||.:     ||....|:.  :......|...|.|
 Frog   407 RSCYQEQMVQTCGCADYQYPL-PNGSEYCS-NDKYPDWVPCYYGLRDSVADRESCISLCQQPCND 469

  Fly   394 VTYS-------------------TLSYKTDLNQHKYSVSRFYSPELLNNDSFVLRVYLAKQVVPV 439
            ..|.                   .|||:.| :.|..:|:|        |....|.:|..:.....
 Frog   470 TQYKMVISMADWPSAGAQDWIFHVLSYEKD-SSHNITVNR--------NGIVRLNIYFQEFNYRS 525

  Fly   440 IRKVTVMSWIGLLSDLGGIFNLCLGLSMISVVEF 473
            |.:....:.:.|||:|||.|...:|.|::.::||
 Frog   526 ITESEATNVVWLLSNLGGQFGFWMGGSVLCIIEF 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:459966	107/516 (21%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	114/554 (21%)