Protein Alignment ppk6 and asic4a

DIOPT Version :10

• Sequence 1: NP_611461.3
• Gene: ppk6 / 37286
• FlyBaseID: FBgn0034489
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_999952.1
• Gene: asic4a / 407668
• ZFINID: ZDB-GENE-040513-5
• Length: 539
• Species: Danio rerio
• Alignment Length: 529
• Identity: 106/529 - (20%)
• Similarity: 193/529 - (36%)
• Gaps: 115/529 - (21%)

  Fly    12 KKNSKGDGSRKRGKDPSLIR------TAILATFWEYTERTKVSGMWLMRRNRTYGLSRFIWSSVL 70
            |:....||.::     |||.      |..||.|...:....::.:::..|   .|:.:.:|:...
Zfish    17 KQKGNQDGDKE-----SLIEESCSPPTKDLAGFASASSLHGINHIFVSGR---LGVRQTLWALAF 73

  Fly    71 LQLLLLSIYLTLLLWLKFYSYPILNTISNDLSITDVAFPGVTICSPKVVNSERVDRY-VKTLKIP 134
            |..|.|.:|......:.:..:|.: |..|:.:..::.||.||||:        ::|: ...|...
Zfish    74 LVSLALFLYQAAKCAISYLEHPHV-TALNEEATPEMVFPAVTICN--------INRFRFSALTDA 129

  Fly   135 KEYDMAEVIAGFDFLNAFTDQSFEPPGHDSYRATDAVLRLNNVSIWEAAMAVSPGCFDYVKRCFW 199
            ..|.:|.:            ....|...|.::.||...             .:|...|...|.
Zfish   130 DIYHLANL------------TGLPPKNKDGHKPTDLEY-------------PAPDMQDIFNRT-- 167

  Fly   200 GHTEFQ----CNQSHEYLS---FIPTTAYLGPCCSFNYNPRNASFVPFSANIFGMDGGLTF---- 253
            ||...:    ||.|.:..|   |.......|.|.:||.|...:.    .....||..||..
Zfish   168 GHQLEEMLKSCNFSGQNCSAEDFTVVYTRYGKCYTFNGNKTTSR----KTKQGGMGNGLEIMLDI 228

  Fly   254 -------VGAEGSERNLNTGLIVLVH--------HPMDYVTEAAASVTITAQSESFVEVSP---T 300
                   :..|.:|.:|..|:.|.:|        |.:.:.........::.|.:....:..   .
Zfish   229 QQDDYLPIWKETNETSLEAGIRVQIHSQDEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGN 293

  Fly   301 VQSSSVEVLELSERKRDCLISGDLQLSNYRQAACLLACQTEAIVKKCGCHPYLLPIVGNKFKECN 365
            .:|:|.:           :|.|   ...|..:||.|.|:|..::::|.|....:|...|   .|.
Zfish   294 CRSTSEQ-----------MIPG---YDTYSISACRLRCETLEVLRECKCRMVHMPGDAN---ICT 341

  Fly   366 LNDTFCYSANYDNFKSVRCDQCLPNCYDVTYSTLSYKTDLNQHKYS-------VSRFY--SPELL 421
            .:|..|........:....|.|.  | :...:...|..:|:..|..       :||.|  |.:.:
Zfish   342 PSDIKCVDKALALLQKSSGDTCF--C-ETPCNLTRYGKELSMVKIPSKGSARYLSRKYDKSEDYI 403

  Fly   422 NNDSFVLRVYLAKQVVPVIRKVTVMSWIGLLSDLGGIFNLCLGLSMISVVEFFYYCTYRLYINYQ 486
            .::..||.::........|.:.......|||.|:||...|.:|.|:::::|...| .|.: |.::
Zfish   404 RDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASVLTILEILDY-VYEV-IKHR 466

  Fly   487 LQKVQQPRK 495
            |:::.:|::
Zfish   467 LERLLRPQR 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:459966	84/429 (20%)
asic4a	NP_999952.1	ENaC	44..472	CDD:273304	96/492 (20%)
		GAS motif, ion selectivity filter. /evidence=ECO:0000250|UniProtKB:P78348	446..448		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	474..494		0/2 (0%)