Protein Alignment ppk6 and scnn1a

DIOPT Version :10

• Sequence 1: NP_611461.3
• Gene: ppk6 / 37286
• FlyBaseID: FBgn0034489
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001184124.1
• Gene: scnn1a / 395013
• XenbaseID: XB-GENE-996083
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 113/554 - (20%)
• Similarity: 217/554 - (39%)
• Gaps: 136/554 - (24%)

  Fly    22 KRGKDPSLIRTAILATFWEYTE-------RTKVSGMWLMRRNRTYGLSRFIWSSVLLQLLLLSIY 79
            |..|:|      ::..|..|.|       .|.:.|...:..:|:..:....|..:.|....|..:
 Frog     6 KNEKEP------LIEFFSSYRELFEFFCSNTTIHGAIRLVCSRSNRMKTAFWLVLFLATFGLMYW 64

  Fly    80 LTLLLWLKFYSYPILNTISNDLSITDVAFPGVTICSPKVVNSERVDRYVKTLKIPKEYDMAEV-- 142
            ...||:.:::|||:  :|:.:::...:.||.||:|:......:.:...::.|....:..:.|:
 Frog    65 QFGLLFGQYFSYPV--SINLNVNSDKLPFPAVTVCTLNPYRYKAIQNDLQELDKETQRTLYELYK 127

  Fly   143 -----IAGFDFLNAFTDQ---------SFEPPGHDSYRATDAVL--------RLNNVSIWEAAMA 185
                 :.|:...|....:         ...|||..::|.:.:|:        |..|:. ::....
 Frog   128 YNSTGVQGWIPTNQRVRRDRPGLPHLLELVPPGSKTHRVSRSVIEEELQVKRREWNIG-FKLCNE 191

  Fly   186 VSPGCF--------DYVKRCFWGH----------------------------TEFQC---NQSHE 211
            ....||        |.::..:..|                            .|..|   |.||.
 Frog   192 TGGDCFYQTYTSGVDAIREWYRFHYINILARVPEEAAIDGEQLENFIFACRFNEESCTKANYSHF 256

  Fly   212 YLSFIPTTAYLGPCCSFNYNPRNASFVPFSANIFGMDGGLTFVGAEGSERNLNTGLIVLVHHPMD 276
            :      .|..|.|.:||.| |:.....:|:::.|:..|||               ::|.....|
 Frog   257 H------HAIYGNCYTFNQN-RSGQSNLWSSSMPGIKNGLT---------------LILRTEQHD 299

  Fly   277 YV----TEAAASVTITAQSE-SFVE-----VSPTVQSS----SVEVLELSERKRDCLISG-DLQL 326
            |:    :.|.|.|.:....| :|::     :.|.:::|    ...|..:..:..||...| |:.:
 Frog   300 YIPLLSSVAGARVLVHGHKEPAFMDDSGFNIPPGMETSIGMKKETVNRMGGKYSDCSEDGSDVDV 364

  Fly   327 SN-----YRQAACLLACQTEAIVKKCGCHPYLLPI-VGNKFKECNLNDTF--CYSANYDNFKS-- 381
            .|     |.:..|:.:|...|:|::|||.....|: .|::|.:.|.:.::  ||......|.|
 Frog   365 KNLFESEYTEQVCVRSCFQAAMVERCGCGYAFYPLSPGDEFCDYNKHKSWGHCYYKLIIEFTSNK 429

  Fly   382 ----VRCDQ-CLPNCYDVT--YSTLSYKTDLNQHKYSVSRFYSPELLNNDSFV-LRVYLAKQVVP 438
                .:|.: ||.:.|.:|  ||....:...:...:::||.|:  |.:.:... |.:|..:....
 Frog   430 LGCFSKCRKPCLVSEYQLTAGYSKWPNRVSQDWVFHTLSRQYN--LTDRNGIAKLNIYFEELNYK 492

  Fly   439 VIRKVTVMSWIGLLSDLGGIFNLCLGLSMISVVE 472
            .|::...::.:.|||.||..::|..|.|::||||
 Frog   493 TIQESPTINMVMLLSLLGSQWSLWFGSSVLSVVE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:459966	99/484 (20%)
scnn1a	NP_001184124.1	ENaC	18..602	CDD:273304	109/536 (20%)