DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk6 and ppk16

DIOPT Version :9

Sequence 1:	NP_611461.3	Gene:	ppk6 / 37286	FlyBaseID:	FBgn0034489	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001334673.1	Gene:	ppk16 / 3885612	FlyBaseID:	FBgn0065108	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	533	Identity:	119/533 - (22%)
Similarity:	212/533 - (39%)	Gaps:	106/533 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GKWPTPGKKNSKGDGSRKRGKDPSLIRTAILATFWEYTERTKVSGMWLMRRNRTYGLSRFIWSSV 69
            |:|.|...:|                          |.:.|.:.|...:.|.......|:.|..|
  Fly    49 GEWFTENMRN--------------------------YCQTTSLHGFSYITRQDISRHERWFWLVV 87

  Fly    70 LLQLLLLSIYLTLLLWLKFYSYPILNTI-SNDLSITDVAFPGVTICSPKVVNSERVDRYVKTLKI 133
            ::..::.||.|.::.|......|.:..| |:.....::.||.||||:...::..:....:..:::
  Fly    88 VILAIITSIVLVVVSWYWSQETPTVTVIESSHFPTWNIPFPAVTICNFNKISKSKALSLLDQMQV 152

  Fly   134 PKEYDMAEVIAGFDFLNAFTDQSFEPPGHDSYRATDAVLRLNNVSIWEAAMAVSPGCFDYVKRCF 198
            |...:.:|:...|:......|...   .:||.:..|.:|.|||:::......:||.|.:.:..|.
  Fly   153 PVGINRSELHNLFNLTLLPVDTMI---SNDSLQKYDRILSLNNLTLNRLTQQLSPDCIEMISSCI 214

  Fly   199 WGHTEFQCNQSHEYLSFIPTTAYLGPCCSFNY-------NPRNASFV----PFSANIFGMDGGLT 252
            |.....:|....:.:..:.     |.||:|||       .|...::.    |:.....|...||:
  Fly   215 WKGINTRCESLFQRIDTME-----GQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTGCGYPTGLS 274

  Fly   253 FVGAEGSERNLNT-------------GLIVLVHHPMDYVTEAAASVTITAQSESFVEVSP--TVQ 302
            .:        ||.             |..:|:|...::..|.:.:..:|...||||.::|  |..
  Fly   275 VL--------LNPMISDYYGTFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPESTYA 331

  Fly   303 SSSVEVLELSERKRDCLISGDLQLSNYRQAA---CLLACQTEAIVKKCGCHPYLLPIVGN--KFK 362
            ::.:..::||  .|:||...::.:...|:.:   |:..|:....|..|||.|   |.|.|  .:|
  Fly   332 TNDIRRMDLS--LRNCLFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLP---PYVYNNGSYK 391

  Fly   363 ECNLNDTFC-------YS---ANYDNFK--------SVRCDQCLPNCYDVTYSTLSYKTDLNQHK 409
            .|.:..|.|       :|   ||. ||.        |..|. |||:|     .:..|.::....:
  Fly   392 VCGVLQTNCIIHSKRLFSHALANL-NFSLSIVRETDSFPCG-CLPDC-----QSNHYVSESTTGR 449

  Fly   410 YSVSRFYSPELLNN--DSFVLRVYLAKQVVPVIRKVTVMSWIGLLSDLGGIFNLCLGLSMISVVE 472
            ..:|.|.:....||  |..:|.|:.:..:....|.....:|:..|:..||:..|.:|.|:::..|
  Fly   450 LDISYFANRPTFNNATDRILLHVFFSDLMSTRYRTDIFQNWLSALASFGGLLGLIMGFSIVTAFE 514

  Fly   473 FFYYCTYRLYINY 485
            |.|:.|:|...||
  Fly   515 FIYFLTFRPVFNY 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:279230	100/442 (23%)
ppk16	NP_001334673.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456712
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	5	4.840