DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk6 and ppk26

DIOPT Version :9

Sequence 1:	NP_611461.3	Gene:	ppk6 / 37286	FlyBaseID:	FBgn0034489	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_648125.3	Gene:	ppk26 / 38835	FlyBaseID:	FBgn0035785	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	548	Identity:	117/548 - (21%)
Similarity:	202/548 - (36%)	Gaps:	121/548 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 AILATFWEYTERTKVSGMWLMRRNRTYGLSRFIWSSVLLQLLLLSIYLTLLLWLKFYSYPILNTI 97
            |..|...||.:.|.:.|:..:...:...|.|..|.|||:..:...:.|||.:|.|:.:.|::.:.
  Fly    66 AAKAIIHEYCDYTTIHGIRYLGEKKRPLLERLFWISVLVLSVFTCVKLTLNIWDKWNNNPVIVSF 130

  Fly    98 S-NDLSITDVAFPGVTICSPKVVNSERVDRYVKTLKIPKEY--------DMAEVIAGFDFLNAFT 153
            : ....:..:.||.||:| |:......:..:..:....:::        |:::...|   |....
  Fly   131 AEKSTPVWQIPFPAVTVC-PETKTRREIFNFTDSYHQVRDFQSNVSGIVDLSDKQKG---LYGAV 191

  Fly   154 DQSFEPPGHDSYRATDAVLRLNN-----VSIWEAAMAVSPGCFDYVKRCFWGHTEFQCNQ-SHEY 212
            .|..||..||        :.|.|     :.|.:|...|||...|....|.|.::..:|:. .|::
  Fly   192 SQVCEPHLHD--------VTLGNKTRRGMEIIDALTEVSPHFDDTYLNCKWRNSPVKCSDIFHKF 248

  Fly   213 LSFIPTTAYLGPCCSFN------------------YNPRN---------------ASFVPFSANI 244
            ::      ..|.|.|||                  :...|               |...|:...:
  Fly   249 VT------EDGVCFSFNSLSPAEIFRAEGIIPDFIFREENRLSMDWNVEDGYSASADTSPYPNRV 307

  Fly   245 FG---MDGGLTFVGAEGSE-------RNLNTGLIVLVHHPMDYVTEAAASVTITAQSESFVEVSP 299
            .|   ..|...|:|  |:|       |....|..:|:|.|.|....:.....|....|..:.:.|
  Fly   308 LGPGARAGLYLFMG--GAEIDFDDMCRGPVQGFKILLHTPGDVAQVSKQYFRIPFDQEVLISIRP 370

  Fly   300 TVQSSSVEVLELSERKRDCLISGDLQL---SNYRQAACLLACQTEAIVKKCGCHPYLLPIVGNKF 361
            .:.::|..:......:|.|....:.:|   :.|.|:.|.|.|.....:.||||..:.:|...| .
  Fly   371 KIITTSDGLKHYEPNRRQCYFQKERELRYFNIYSQSNCELECLANFTLTKCGCVKFSMPRNVN-M 434

  Fly   362 KECNLNDTFCYSANYDNF-----------------KSVRCDQCLPNCYDVTY------STLSYKT 403
            ..|......||:...|..                 ....|: |||:|..:.|      :...|||
  Fly   435 PVCGDASLKCYNQAEDELLLREFTQGLVNAGENTRGETECN-CLPSCTSIAYEAEISQADFDYKT 498

  Fly   404 DLNQHKYSVSRFYSPELLNNDS-------FVLRVYLAKQVVPVIRKVTVMSWIGLLSDLGGIFNL 461
            .:|..        |||.....|       ..:.::..:......|:..:......|::.||:..|
  Fly   499 VINTD--------SPEGKEEQSKRQGMKMSRVSIFFKEAQFLTSRRSELYGTTDFLANCGGLLGL 555

  Fly   462 CLGLSMISVVEFFYYCTYRLYINYQLQK 489
            .:|:||:|:||..|:||.||..|.::::
  Fly   556 FMGVSMLSIVELIYFCTVRLISNLRMRR 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:279230	96/481 (20%)
ppk26	NP_648125.3	ASC	74..570	CDD:279230	108/525 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456720
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D112386at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	6	5.850