DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk6 and ppk17

DIOPT Version :9

Sequence 1:	NP_611461.3	Gene:	ppk6 / 37286	FlyBaseID:	FBgn0034489	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001285988.1	Gene:	ppk17 / 35006	FlyBaseID:	FBgn0032602	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	100/503 - (19%)
Similarity:	167/503 - (33%)	Gaps:	151/503 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 FWEYTERTKVSGMWLMRRNRTYGLSRFIWSSVLLQLLLLSIYLTLLLWLKFYSYPILNTISNDLS 102
            :|..|.      .||.|....  |.|::   ||....::.|......:.|.|:.||.......|:
  Fly     3 YWSETR------AWLFRDPAK--LIRYL---VLFACCIVVIVQLYECFAKLYNPPISTHSYYSLN 56

  Fly   103 ITDVAFPGVTICSPKVVNSERVDR-------YVKTLKIPKEYDMAEVIAGFDFLNAFTDQSFEPP 160
            .| :..|.||||.......|.:.|       :.|......:|...|:         ..|:.||..
  Fly    57 ET-IEMPSVTICREPPYKEEVLTRLSGGACPHPKYATCWMKYPFGEI---------SLDEFFENS 111

  Fly   161 GHDSYRATDAVLRLNNVSIWEAAMAVSPGCFDYVKRCFWGHTEFQCN-QSHEYLSFIPTTAYLGP 224
            .|||   .|..:                         |:|..|.:.| ..:..|.|     |:|.
  Fly   112 THDS---GDTFV-------------------------FYGLNEDKNNVVMNSSLHF-----YMGR 143

  Fly   225 CCSFNYNPRNASFVPFSANIFGMDGGLTFVGAEGSER-NLNTGLIVLVHHPMDYVTEAAASVT-- 286
            |  :...|:                       |.::| :...|..:::.|.|  :|.:.:.|.
  Fly   144 C--YTLRPK-----------------------ESAKRVSKAVGYSIMLEHSM--LTTSVSDVDTG 181

  Fly   287 -------ITAQSESFVEV----SPTVQSSSVEVLELSERKRDCLISGDLQL--------SNYRQA 332
                   |..:.|:|.|:    |..|:...|.|.|..|.|.......::|.        .||...
  Fly   182 SVGWHVFIHDKKENFTEINMKGSGRVEYVFVGVNEEIEIKLQTQYFSNVQTREEACSDDENYSDL 246

  Fly   333 ACLLACQTEAIVKKCGCH-PYLLPIVGNKFKECN--------LNDTFCYSANYDNFKSVRCDQCL 388
            .|...|..:.:.....|. |::..|..   :.||        ::|   |...|:|.....|| |:
  Fly   247 KCGEQCIWQDLADNMQCSGPWMHEIAS---EPCNDSLSMRKLISD---YKDVYENEDDFDCD-CV 304

  Fly   389 PNCYDVTYSTLSYKTDLNQHKYSVSRFYSPELLNNDSFVLRVYLAKQVVPVIRKVTVMSWIGLLS 453
            ..|....|:|.     :...|    .|..||....    :.:|...:::.:|.:.........::
  Fly   305 QPCQSRIYTTF-----IQNRK----AFNQPEPRTQ----IYIYYTTKLISMIEERPSYDTTQFIA 356

  Fly   454 DLGGIFNLCLGLS---MISVVE--FFYYCTYRLYINYQLQKVQQPRKA 496
            |:||.....||||   :|.::|  ..::|      ...::::||..:|
  Fly   357 DVGGSLGFLLGLSVLGLIGILEHMMLFFC------GGFIKRMQQKEQA 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk6	NP_611461.3	ASC	85..476	CDD:279230	86/434 (20%)
ppk17	NP_001285988.1	ASC	11..358	CDD:295594	84/441 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456708
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930